OR8I2
Identifiers
AliasesOR8I2, OR11-170, olfactory receptor family 8 subfamily I member 2
External IDsMGI: 3030938 HomoloGene: 64916 GeneCards: OR8I2
Orthologs
SpeciesHumanMouse
Entrez

120586

258763

Ensembl

ENSG00000172154

ENSMUSG00000075166

UniProt

Q8N0Y5

A2AVB5

RefSeq (mRNA)

NM_001003750

NM_146767

RefSeq (protein)

NP_001003750

NP_666978

Location (UCSC)Chr 11: 56.09 – 56.09 MbChr 2: 86.85 – 86.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 8I2 is a protein that in humans is encoded by the OR8I2 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000172154 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000075166 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: OR8I2 olfactory receptor, family 8, subfamily I, member 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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