OR4F5

OR4F5
Identifiers
Aliases	OR4F5, olfactory receptor family 4 subfamily F member 5
External IDs	HomoloGene: 128250 GeneCards: OR4F5
Gene location (Human)
Chr.	Chromosome 1 (human)
End	71,585 bp
RNA expression pattern
	Top expressed in
	ovary; ; muscle of leg; ; esophagus; ; gastrocnemius muscle; ; stomach; ; body of stomach; ; colon;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	79501
	n/a
	ENSG00000186092
	n/a
	Q8NH21
	n/a
	NM_001005484
	n/a
	NP_001005484
	n/a
	Wikidata
View/Edit Human

Olfactory receptor family 4 subfamily F member 5 is a protein that in humans is encoded by the OR4F5 gene. ^[3]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Trivia

OR4F5 is the first protein coding gene on human chromosome 1.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000186092 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Olfactory receptor family 4 subfamily F member 5".

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000186092 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: Olfactory receptor family 4 subfamily F member 5".

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