OR51A7
Identifiers
AliasesOR51A7, OR11-27, olfactory receptor family 51 subfamily A member 7
External IDsMGI: 3030410 HomoloGene: 45856 GeneCards: OR51A7
Orthologs
SpeciesHumanMouse
Entrez

119687

258248

Ensembl

ENSG00000176895

ENSMUSG00000073962

UniProt

Q8NH64

n/a

RefSeq (mRNA)

NM_001004749

NM_001001805

RefSeq (protein)

NP_001004749

n/a

Location (UCSC)Chr 11: 4.9 – 4.91 MbChr 7: 102.61 – 102.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 51A7 is a protein that in humans is encoded by the OR51A7 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

As of 2015, OR51A7 was an orphan receptor, meaning that no odorants have been identified which bind to it.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000176895 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000073962 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: OR51A7 olfactory receptor, family 51, subfamily A, member 7".
  6. ↑ de March CA, Ryu S, Sicard G, Moon C, Golebiowski J (September 2015). "Structure–odour relationships reviewed in the postgenomic era". Flavour and Fragrance Journal. 30 (5): 342–361. doi:10.1002/ffj.3249.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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