Small nucleolar RNA SNORA62/SNORA6 family
Identifiers
SymbolSNORA62
Alt. SymbolsE2
RfamRF00091
Other data
RNA typeGene; snRNA; snoRNA; H/ACA-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000594
PDB structuresPDBe

In molecular biology, Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs.[1]

E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA.[2] E2 is encoded in introns in the gene for a laminin-binding protein.[3]

This family also contains the related ACA6, M2 and MBI-136 snoRNAs.[2][4]

References

  1. Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.
  2. 1 2 Mishra RK, Eliceiri GL (May 1997). "Three small nucleolar RNAs that are involved in ribosomal RNA precursor processing". Proceedings of the National Academy of Sciences of the United States of America. 94 (10): 4972–7. Bibcode:1997PNAS...94.4972M. doi:10.1073/pnas.94.10.4972. PMC 24615. PMID 9144174.
  3. Selvamurugan N, Eliceiri GL (November 1995). "The gene for human E2 small nucleolar RNA resides in an intron of a laminin-binding protein gene". Genomics. 30 (2): 400–1. PMID 8586453.
  4. Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
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