Early life and education

Pyotr Borisovich Gannushkin was born in the Russian Empire in 1875 in the village of Novosyolki in the Pronsk district of the Ryazan Governorate (the present-day Ryazan Oblast). His father Boris was a physician, a compassionate and precise man. His mother Olga (née Mozharova) came of an impoverished Russian landed family. Well-bred and educated, she was fluent in French and German, interested in philosophy, and fond of music, poetry and art. She was, moreover, a gregarious and kind-hearted woman.^[4][5]

In his early years, Pyotr was educated by his mother. After a while, the family moved to Ryazan, the regional capital, where his father started teaching at a high school for boys. Soon after his 9th birthday, the young Gannushkin enrolled at the same school. An excellent student, Pyotr was always sociable, honest, and inclined to irony; he nursed a dislike for severe discipline. During his school years, he edited his own home journal.^[6]

Gannushkin's sister Maria noted in her memoirs that Pyotr never told anyone which profession he intended to pursue. When he turned 13, however, Gannushkin's keen interest in "personology" and human mentality became apparent. It was then that he read Sechenov's 1863 monograph "Brain Reflexes", a successful attempt to describe the physiological mechanisms of mental activity.

University years

In 1893 Gannushkin graduated from the high school with a gold medal, the highest award, and entered the department of medicine at Moscow State University. In his third year of studies, he finally decided to become a psychiatrist after being influenced by such university professors as Aleksei Kozhevnikov and Sergei Korsakoff.

All the students, including Gannushkin, were fascinated by the way Korsakoff interacted with the mentally disabled. As Korsakoff explained, "mental patients should not be regarded as soulless creatures: they should be considered personalities familiar to everyone who is somehow related to them."^[7]

In addition to attending lectures and recitals during his university years, Gannushkin served as an orderly with the responsibilities of a junior medical staff member.^[8][9]

Collaboration with Sergei Sukhanov

Korsakoff's assistant Sergei Sukhanov was willing to help young physicians, fostering them in word and in deed. Sukhanov was a proponent of the nosological approach. He demonstrated a remarkable power of observation. Borderline psychiatry, especially psychopathies and psychogenies, was among his main research interests. His inclination towards synthesis led Sukhanov to note both the scientific and social importance of this problem.

Sukhanov managed to stir Gannushkin's interest in these issues and the two developed friendly relations, publishing six research papers together. They preferred to study individual mental disorders rather than their mixed types, believing that this approach would contribute to the study of acknowledged diseases, the discovery of new mental disorders, and the development of psychiatric taxonomy. Sukhanov and Gannushkin distinguished a particular form of obsession and were the first to show the process whereby, at least in some cases, obsessions were transformed into schizophrenia.^[13]

Acute paranoia (1904)

In 1904, Gannushkin submitted his thesis on "Acute paranoia" (Russian: Острая паранойя). It took the form of a sketch of the historical development of the theory of acute paranoia. The thesis opened with a description of the research of Vincenzo Chiarugi and Jean-Étienne Dominique Esquirol. The focus then shifted to works by Wilhelm Griesinger, Bénédict Morel, and Karl Friedrich Otto Westphal. Next Gannushkin presented observations made by Sergei Korsakoff, Vladimir Serbsky, Emil Kraepelin, and Eugen Bleuler. Finally Gannushkin gave a brilliant exposition of his own findings about paranoia.^[4][14]

After his thesis was accepted and approved, Gannushkin became a privat dozent (i.e. freelance university lecturer) of the Department of Mental Disorders in the Moscow State University. It was then that he began to deliver his course of lectures on "The Theory of Pathological Characters" (Russian: Учение о патологических характерах).

In 1905, Gannushkin attended courses in postgraduate psychiatry at Kraepelin's clinic in Munich. Thereafter he became a proponent of Kraepelin's theory. The following year, Gannushkin visited St. Anne's Psychiatric Hospital (French: Hôpital Sainte-Anne) in Paris, where he familiarized himself with the work of Valentin Magnan, an influential figure in French psychiatry. In 1908 and in 1911 Gannushkin again attended postgraduate psychiatry courses at Kraepelin's clinic.

Resignation (1911) and post-Revolutionary career

In 1911 university autonomy became a crucial issue in Russia, leading to repressive measures by the Tsar's protégé Lev Kasso, the education minister. In 1911, together with other progressive scholars and scientists, Gannushkin left the university in protest. From 1906 until 1914, when he was drafted into the army, he worked as a resident physician at the Moscow Alexeyev Psychiatric Hospital (Russian: Московская Алексеевская психиатрическая больница), known today as the Kashchenko Mental Hospital (Russian: больница имени П. П. Кащенко). During this period Gannushkin and others set up a first-class research journal, The Korsakoff Journal of Neuropathology and Psychiatry (Russian: Журнал невропатологии и психиатрии имени Корсакова).

In 1917, after being discharged from the army for health reasons,Gannushkin returned in the Moscow Alexeyev Psychiatric Hospital. From 1918 onwards he was a professor in the Department of Psychiatry at the Moscow State University (from 1930 he was professor at the I.M. Sechenov First Moscow State Medical University) and director at the University Psychiatric Hospital: today this is known as the Korsakov Clinic of Psychiatry at the Sechenov Moscow Medical Academy (Russian: Клиника имени С. С. Корсакова АМН России имени И. М. Сеченова).

Some other aspects of his work

Gannushkin was one of the first psychiatrists to talk about the schizoid reaction type, the somatogenic and psychogenic reactions of schizoids.

In 1927, he identified the "epileptoid reaction type", which is usually characterized by repeated temporary reactions caused by the influence of psychogenic factors and unfavorable situations. This reaction type is expressed by symptoms of dysphoria, i.e. malicious actions combined with anger, anguish, and fear.^[15] In many ways, this reaction type is akin to the behavior pattern typical for borderline personality disorder. As a psychotic episode, such reactions could happen during epidemic encephalitis, cerebral atherosclerosis, and brain injury.

Gannushkin also took part in the experimental study of hypnosis. He criticized Lombroso's theory of crime.^[16]

Gannushkin was interested in psychoanalytical ideas, and made experimental use of psychoanalytic therapy. His stance on psychoanalysis is outlined in his "On Psychotherapy and Psychoanalysis" (Russian: О психотерапии и психоанализе).^[17] Not a committed proponent of Freud's theory, Gannushkin did believe that under certain conditions psychoanalytical methods could be used as part of the process of treatment.^[11][18]

Gannushkin regarded war and revolution as a "traumatic epidemic" affecting the entire population. There is a reciprocal influence, he used to say, between the mentality of the population and its life in society.^[2][19]

Under Gannushkin's direction a new form of medical care for people with mental disorders was created in Russia. He helped to organise a network of psychoneurological out-patient clinics in the USSR. He worked on issues linked to the teaching of psychiatry and the prevention of mental illness.^[20]

Gannushkin's granddaughter Svetlana Gannushkina, mathematician and noted human rights activist.

A Moscow river embankment is named after Pyotr B. Gannushkin.

Marriage, son and grand-daughter

Pyotr Borisovich Gannushkin married the pianist Sofia Vladimirovna Klumova (1880-1945). They had one son Alexey Petrovich Gannushkin (1920-1974) who was an aircraft design engineer, USSR State Prize Laureate, and father of Svetlana Gannushkina (b. 1943).

Svetlana Alexeyevna Gannushkina is a mathematician and human rights activist, working particularly to help immigrants and refugees through the Civic Assistance NGO.^[21][22] (She was reported to be a serious contender for the 2010 Nobel Peace Prize.) ^[23] A professor of mathematics at the Historical Archives Institute between 1970 and 1999, Gannushkina was a member of the presidential Council for the Development of Civil Society Institutions and Human Rights until her resignation in June 2012.

Personality and views on psychiatry

Gannushkin was a modest and diffident man and he disliked public speaking. When attending psychiatric conferences, he preferred to stay in the background. Only among fellow scientists and when lecturing to his senior students was Gannushkin able to speak his mind. An experienced clinician, he was a proponent of the natural science method who considered himself an enemy of pompous and meretricious declamation.^[24][25]

Gannushkin's power of observation was enhanced by his erudition and ability to discern the most useful points in a variety of different monographs and articles. He recorded each new thought and accurately gathered all required materials. His lectures and clinical vignettes show how carefully he scrutinized and systematized all the research data he was working with.^[18]

As L.A. Prozorov commented: "Gannushkin could stir the interest of young people in research, even if it was crude; he sought out and selected research scientists."^[26] Remembering her husband, Sophia Gannushkina said, "Once he decided to do something, he grew fearless."

Throughout his life, Gannushkin believed that psychiatry and our life in society are closely connected. To him a psychiatrist was primarily a community worker. That is why, perhaps, he made psychopathies his main research subject.

"Our generation does not limit itself to psychiatric hospitals. Using the same approach, we visit schools, barracks, and prisons. We are not looking for those who need to be hospitalized, but for the half-normal, borderline types, those who represent intermediate steps. Borderline psychiatry, minor psychiatry... - here is a motto for our times, an area to which our actions must be directed in the immediate future."^[19]

Death and influence

While Gannushkin was finishing his seminal work on the Manifestations of psychopathies: their statics, dynamics and systematic aspects (Russian: Клиника психопатий, их статика, динамика, систематика), his health quickly deteriorated. After long hesitation he agreed to undergo the proposed operation. The best Russian surgeons and physicians tried to save him, but he died on 23 February 1933. Before his death he managed to read his monograph after proofreading and approve it for publication. The book appeared that year following his death.^[4]

Research papers written by Gannushkin and his followers represent a landmark in the theory of psychopathies in Russia. Among Russian psychiatrists, it was Gannushkin who developed the most accurate definition of various psychopathies (personality disorders).^[27] Gannushkin had many followers, among who it is possible to distinguish three generations.

The first generation of disciples was formed of colleagues who worked under his direction: D.A. Amenitsky, I.N. Vvedensky, T.A. Geyer, V.A. Grombakh, M.O. Gurevich, P.M. Zinovyev, E.K. Krasnushkin, L.A. Prozorov, L.M. Rezenstein, M.Y. Serieysky, T.I. Yudin. The second generation was made up of Gannushkin's senior students: B.A. Belousov, A.G. Galachyan, F.F. Detengor, S.G. Zhislin, A.N. Zalmanov, M.Z. Kaplinsky, R.E. Lusternik, N.S. Molodenkov, A.N. Molokhov, N.I. Ozeretsky, D.S. Ozeretskovsky, T.P. Simpson, Y.A. Florenskaya, B.D. Fridman, Y.P. Frumkin, A.O. Edelstein. A third generation included his junior students (A.P. Alexandrova, A.M. Dubinin, O.V. Kerbikov, S.V. Krayts, A.Y. Levinson, D.E. Melekhov, V.M. Morozov, A.I. Ponomoryov, B.A. Famin, P.D. Fridman, Y.D. Shulman). Together, Gannushkin's followers made significant contributions to the development of psychiatry in Russia.^[28][29]

In 1933, the Health Care Commissariat's Research Institute of Neuropsychiatric Treatment established an annual Gannushkin award.^[30][31] In 1936, Moscow's Psychiatric Hospital No.4 was named after Gannushkin (Russian: Психиатрическая клиническая больница № 4 им. П.Б. Ганнушкина). Later a Gannushkin memorial museum was created inside the hospital. A river embankment in Moscow was also renamed in his honor.^[32][33]

Gannushkin was immortalised in fiction as Professor Titanushkin, a character in Ilf and Petrov's satirical novel The Little Golden Calf (1931).