Vladimir Baranov Scientist

Vladimir Baranov is a Soviet born Canadian scientist and one of the original co-inventors of Mass cytometry technology...[1]

He co-founded DVS Sciences[2] in 2004 (acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022[3]) along with Dmitry Bandura,Scott D. Tanner and Olga Ornatsky.

Biography

In 1993, he immigrated to Canada. Prior to the formation of DVS Sciences. Dr. Baranov, a Senior Scientist at MDS SCIEX, was a key member of the research team that developed and promoted the Dynamic Reaction Cell®, which remains today at the pinnacle of quadrupole ICP-MS technology.

In 2005, together with Scott D. Tanner and Dmitry Bandura, he began independently developing an ICP-TOF-MS based cytometer and became a researcher at the University of Toronto in March 2005.[4] After securing ample funding by 2010 from various sources, including National Institutes of Health, Ontario Institute for Cancer Research (OICR), the Ministry of Research and Innovation, Ontario Centres of Excellence, Health Technology Exchange, and Genome Canada via the Ontario Genomics Institute,[5][6][7] and venture capital from 5 AM Ventures,[8] Vladimir and the DVS Sciences team successfully commercialized their technology, leading to the acquisition of DVS Sciences by Fluidigm in 2014[9]

Dr. Baranov was a Principal Scientist at DVS Sciences (and then Fluidigm) developing instrumental concepts and algorithmics that advance the CyTOF® line of products. He also and played a fundamental role in the development of the MaxPar line of metal-labeling reagents until his retirement in 2019.

Education

Career

  • Assistant to the Chair of Physical Chemistry at Moscow State University.[10]
  • Research Associate at York University[10]
  • Senior Scientist at MDS SCIEX[10]
  • Associate Professor at UofT in IBBME (2005-2008) and Chemistry (2008-2011).[4]
  • Adjunct professor at York University.
  • Principal Scientist at DVS Sciences - 2005 - 2019[11]
    (acquired by Fluidigm in 2014 and then Standard BioTools in 2022)

Research

  • Quadrupole theory (stability, acceptance and transmission of multipole RF and electrostatic driven devises), molecular gas dynamics, and supersonic beam expansion into vacuum.
  • Development of the DRC Collision/reaction cell.[12]
  • Development of mass spectrometry (CyTOF), including fundamentals of operation and design of different MS instrumentation.

Awards and honors

Publications

  • Feb 2017 - Imaging Mass Cytometry.[19]
  • Sept 2010 - Highly Multiparametric Analysis by Mass Cytometry.[20]
  • July 2009 - Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry[21]
  • Aug 2007 - Polymer‐Based Elemental Tags for Sensitive Bioassays.[22]
  • Sept 2002 - Reaction Cells and Collision Cells for ICP-MS: a tutorial review.[23]
  • May 2002 - A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection.[24]
  • Feb 2002 - Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell.[25]
  • July 2001 - Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS.[26]
  • Jan 2000 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III. Optimization and Analytical Performance.[27]
  • Nov 1999 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Produced within the Cell.[28]
  • March 1999 - Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS.[29]
  • Feb 1997 - Activation of Hydrogen and Methane by Thermalized FeO+ in the Gas Phase as Studied by Multiple Mass Spectrometric Techniques.[30]

A more complete listing of his publications can be found on Google Scholar

References

  1. ↑ "US Patent 7,135,296". Google Patents. 2000-12-28. Retrieved 6 December 2022.
  2. ↑ "Co-Founded DVS Sciences". MaRSdd.com. 2011.
  3. ↑ "Fluidigm Renamed to Stanard BioTools". Globenewswirel (Press release). 2022-04-04. Retrieved 9 December 2022.
  4. 1 2 "Vladimir Baranov at the University of Toronto". Sunshine List Stats. Retrieved 20 Aug 2023.
  5. ↑ Fong, Tony (May 21, 2010). "Univ. of Toronto Spinout Rolls Out New Biomarker System with Eye on Bead Array Market". Genome Web. Retrieved 29 March 2023.
  6. ↑ OICR (2009). "OICR Annual Report 2008/09" (PDF).
  7. ↑ "Co-Founder of DVS Sciences". MaRSdd.com. 2011.
  8. ↑ "DVS Sciences Raises $14.6 Million in Series A Financing to Advance Commercialization of Novel Single-Cell Analysis Technology" (PDF). 5amventures.
  9. ↑ Bunting, Michaeline (January 29, 2014). "Fluidigm To Acquire DVS Sciences". Standard BioTools. Retrieved 29 March 2023.
  10. 1 2 3 4 5 "Vladimir Baranov Biography". 2009. Archived from the original on 2009-06-19.
  11. ↑ "Principal Scientist - DVS Sciences". 2014. Archived from the original on 2014-02-28.
  12. ↑ Scott D. Tanner; Vladimir Baranov; Dmitry Bandura (2002). "Reaction cells and collision cells for ICP-MS: a tutorial review". Spectrochimica Acta B. 57 (9): 1361–1452. Bibcode:2002AcSpe..57.1361T. doi:10.1016/S0584-8547(02)00069-1.
  13. ↑ "HUPO Awards - 2019 RECIPIENTS". HUPO. 2019.
  14. ↑ "CyTOF Inventors Receive Prestigious Science and Technology Award from the Human Proteome Organization (HUPO)". Bloomberg.com. Bloomberg. September 18, 2019.
  15. ↑ Nicolò Omenetto; Greet de Loos (20 September 2004). "Elsevier/Spectrochimica Acta Atomic Spectroscopy Award 2002". Spectrochimica Acta Part B: Atomic Spectroscopy. 59 (9): 1335. Bibcode:2004AcSpe..59.1335O. doi:10.1016/j.sab.2004.08.002. ISSN 0584-8547.
  16. ↑ "Manning Awards - Award of Distinction". Manningawards. 2001. Archived from the original on 2016-08-17.
  17. ↑ Gwyn Morgan (Feb 8, 2010). "Manning Award laureates on the cutting edge". TheGlobeAndMail.com. The Globe and Mail. Archived from the original on 2014-02-14.
  18. ↑ "1999 Pittcon Editors' Awards". OOcities.org. May 1999.
  19. ↑ Qing Chang; Olga I. Ornatsky; Iram Siddiqui; Alexander Loboda; Vladimir I. Baranov; David W. Hedley (September 2017). "Imaging Mass Cytometry". Cytometry Part A, the Journal of Quantitative Single-cell Analysis. 91 (2): 160–169. doi:10.1002/cyto.a.23053. PMID 28160444. S2CID 29523347.
  20. ↑ Olg Ornatsky; Dmitry Bandura; Vladimir Baranov; Mark Nitz; Mitchell A Winnik; Scott D.Tanner (September 2010). "Highly Multiparametric Analysis by Mass Cytometry". Journal of Immunological Methods. Elsevier. 361 (1–2): 1–20. doi:10.1016/j.jim.2010.07.002. PMID 20655312.
  21. ↑ Dmitry R Bandura; Vladimir Baranov; Olga Ornatsky; Alexei Antonov; Robert Kinach; Xudong Lou; Serguei Pavlov; Sergey Vorobiev; John E Dick; Scott D. Tanner (July 2009). "Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry". Analytical Cchemistry. American Chemical Society. 81 (16): 6813–6822. doi:10.1021/ac901049w. PMID 19601617.
  22. ↑ Xudong Lou; Guohua Zhang; Isaac Herrera; Robert Kinach; Olga Ornatsky; Vladimir Baranov; Mark Nitz; Mitchell Winnik (August 2007). "Polymer-Based Elemental Tags for Sensitive Bioassays". Angewandte Chemie International Edition. WILEY-VCH Verlag Weinheim. 46 (32): 6111–6114. doi:10.1002/anie.200700796. PMC 2504858. PMID 17533637.
  23. ↑ Scott D. Tanner; Vladimir I. Baranov; Dmitry R. Bandura (September 2002). "Reaction Cells and Collision Cells for ICP-MS: a tutorial review". Spectrochimica Acta Part B: Atomic Spectroscopy. Elsevier. 57 (9): 1361–1452. Bibcode:2002AcSpe..57.1361T. doi:10.1016/S0584-8547(02)00069-1.
  24. ↑ Vladimir Baranov; Zoe Quinn; Dmitry R. Bandura; Scott D. Tanner (May 2002). "A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection". Analytical Chemistry. American Chemical Society. 74 (7): 1629–1636. doi:10.1021/ac0110350. PMID 12033255.
  25. ↑ Dmitry R. Bandura; Vladimir I. Baranov; Scott D. Tanner (February 2002). "Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell". Analytical Chemistry. ACS Publications. 74 (7): 1497–1502. doi:10.1021/ac011031v. PMID 12033236.
  26. ↑ Dmitry R. Bandura; Vladimir I. Baranov; Scott D. Tanner (July 2001). "Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS". Fresenius' Journal of Analytical Chemistry. Springer-Verlag. 370 (5): 454–470. doi:10.1007/s002160100869. PMID 11496972. S2CID 20007527.
  27. ↑ Scott D. Tanner; Vladimir I. Baranov; Uwe Vollkopf (January 2000). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III. Optimization and Analytical Performance". Journal of Analytical Atomic Spectrometry. Royal Society of Chemistry. 15 (9): 1261–1269. doi:10.1039/b002604m.
  28. ↑ Scott D. Tanner; Vladimir I. Baranov (November 1999). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Produced within the Cell". Journal of the American Society for Mass Spectrometry. Springer-Verlag New York. 10 (11): 1083–1094. doi:10.1016/S1044-0305(99)00081-1. S2CID 93608392.
  29. ↑ Scott D. Tanner; Vladimir I. Baranov (March 1999). "Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS". Atomic Spectroscopy - Norwalk Connecticut. Atomic Spectroscopy. 20: 45–52.
  30. ↑ Detlef Schröder; Helmut Schwarz; David E. Clemmer; Yumin Chen; P.B. Armentrout; Vladimir I. Baranov; Diethard K. Böhme (Feb 1997). "Activation of Hydrogen and Methane by Thermalized FeO+ in the Gas Phase as Studied by Multiple Mass Spectrometric Techniques". International Journal of Mass Spectrometry and Ion Processes. Elsevier. 161 (1–3): 175–191. Bibcode:1997IJMSI.161..175S. doi:10.1016/S0168-1176(96)04428-X.
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