Names | |
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Preferred IUPAC name
5-(Aminomethyl)-1,2-thiazol-3-ol | |
Identifiers | |
3D model (JSmol) |
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PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C4H6N2OS | |
Molar mass | 130.17 g·mol−1 |
Melting point | 140 °C (decomp.)[1] |
Acidity (pKa) | 6.06 ± 0.03, 8.85 ± 0.04 (H2O, 21 °C) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
Thiomuscimol is a GABAA receptor agonist which is structurally related to muscimol.[2]
References
- ↑ Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg, Thomas; Pilotti, Anne-Marie; Anthonsen, T. (1976). "Structural Analogues of GABA. Synthesis of 5-Aminomethyl-3-isothiazolol (Thiomuscimol)". Acta Chemica Scandinavica. 30b: 781–785. doi:10.3891/acta.chem.scand.30b-0781.
- ↑ Krogsgaard-Larsen, P; Hjeds, H; Curtis, DR; Lodge, D; Johnston, GA (1979). "Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues". Journal of Neurochemistry. 32 (6): 1717–24. doi:10.1111/j.1471-4159.1979.tb02284.x. PMID 448364. S2CID 1393563.
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