Sharon K. Inouye
Born
Culver City, California, USA
Spouse
Stephen Lewis Helfand
​
​
(m. 1983)​
Academic background
EducationBA, English literature, 1977, Pomona College
MD, 1981, UCSF Medical Center
MPH, 1989, Yale University
Academic work
InstitutionsHarvard Medical School
Yale University

Sharon Kiyomi Inouye is an American geriatrician. She is the Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research, as well as a professor of medicine at the Harvard Medical School and Beth Israel Deaconess Medical Center. Her career has focused on maintaining healthy brain aging, preventing delirium and functional decline, and optimizing healthcare for older adults. Her recent work has focused on healthy longevity and combating ageism.[1]

Early life and education

Inouye was born to parents Lily Ann and Mitsuo Inouye in Culver City, California, the second of four children.[2] She attended Pomona College for her undergraduate degree where she majored in English literature before studying medicine at the UCSF Medical Center, matriculating there as the youngest of her class.[3] She completed her internal medicine residency as UCSF and Beth Israel Deaconess Medical Center (Harvard). As a senior resident in internal medicine at Moffitt Hospital in 1983, she married neurobiologist Stephen Lewis Helfand.[2]

Career

Upon completing her medical degree, Inouye completed a post-doctoral research fellowship in general medicine at Stanford with Dr. Harold Sox prior to completing the Robert Wood Johnson Clinical Scholars Program at Yale with Drs. Alvan Feinstein and Ralph Horwitz, where she completed an MPH degree in 1989.[4] She joined the faculty at Yale University from 1985 to 2005.[5] As a professor at Yale, she focused on translating clinical investigation from its theoretical basis to practical applications that will improve clinical care and quality of life for older persons.[6] In the 1990s, she focused her research on preventing delirium amongst the elderly in hospitals. As such, she developed the Confusion Assessment Method as a new tool for the identification of delirium in 1990, now the most widely used tool for identification of delirium worldwide.[7] In 1999, she published a landmark study in the New England Journal of Medicine demonstrating a 40% reduction in delirium using a multi-component non-pharmacologic program targeted at delirium risk factors.[8] These strategies, which included orientation, early mobilization, providing nutrition and hydration, and enhancing sleep without medication using warm milk and backrubs, were encapsulated in the Hospital Elder Life Program (HELP).[9] Yale-New Haven Hospital adopted her prevention methods such as warm milk and backrubs as a routine method.[10] She also developed the Hospitals Elder Life Program (HELP) to prevent delirium in hospitalized patients.[11] By 2002, Inouye was serving as Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research and was the Milton and Shirley F. Levy Family Chair at Yale. As a result of her research, she was elected a member of the American Society for Clinical Investigation.[12] Inouye was then awarded the 2003 Ewald W. Busse Research Award in Biomedical Sciences,[6] the 2005 Leonard Tow Humanism in Medicine Award (Arnold P. Gold Foundation),[13] and elected to the Society of Distinguished Teachers, Yale University School of Medicine, in 2005.[1] Inouye was a tenured full professor at Yale, director of the Yale Mentored Clinical Research Scholars Program, co-director of the Yale Program on Aging, and Claude D. Pepper Older Americans Independence Center, director of the Yale Mentorship Program in Patient-Oriented Research on Aging, and director of Patient-Oriented Research for the Yale Investigative Medicine Program.[1] She was also appointed co-director of the Yale Program on Aging and Yale's Claude D. Pepper Older Americans Independence Center.[14]

Inouye left Yale University in 2005 to join the Beth Israel Deaconess Medical Center, Harvard Medical School, and Hebrew SeniorLife. In 2012, she was elected a member of the National Academy of Medicine.[15] A few years later, Inouye was recognized by Thomson Reuters ScienceWatch as being amongst the world's most influential scientific minds for 2014.[16] In October 2016, Inouye received a federal grant to help establish an interdisciplinary Network for Investigation of Delirium across the United States.[17] Later that year, she also earned the M. Powell Lawton Award for her significant contributions in gerontology.[18] In 2017, Inouye was named a 2017 Health and Aging Policy Fellow and an American Political Science Association Congressional Fellow.[19]

During the COVID-19 pandemic, Inouye was selected as the Next Avenue 2020 Influencer in Aging, in part because of her work advocating for older adults during the COVID-19 pandemic.[20]

She was named editor-in-chief of JAMA Internal Medicine effective July 1, 2023.[21]

References

  1. 1 2 3 "Sharon K. Inouye, M.D., M.P.H. | Hinda and Arthur Marcus Institute for Aging Research". www.marcusinstituteforaging.org. Retrieved 2022-09-13.
  2. 1 2 "Dr. S. L. Helfand Wed To Dr. Sharon Inouye". The New York Times. August 29, 1983. Retrieved October 18, 2021.
  3. ↑ "Meet our Overall Principal Investigator: An Interview with Sharon K. Inouye, MD, MPH" (PDF). Marcus Institute For Aging Research. May 2011. Retrieved October 18, 2021.
  4. ↑ "Sharon K. Inouye, M.D., M.P.H." www.hebrewseniorlife.org. Retrieved 2022-09-13.
  5. ↑ "Who We Are: Sharon K. Inouye, M.D., M.P.H." Marcus Institute For Aging Research. Retrieved October 18, 2021.
  6. 1 2 Peart, Karen (February 4, 2004). "Three Yale Researchers Win National Awards in Aging". Yale School of Medicine. Retrieved October 18, 2021.
  7. ↑ Inouye, S. K.; Van Dyck, C. H.; Alessi, C. A.; Balkin, S.; Siegal, A. P.; Horwitz, R. I. (December 15, 1990). "Clarifying confusion: the confusion assessment method. A new method for detection of delirium". Annals of Internal Medicine. 113 (12): 941–948. doi:10.7326/0003-4819-113-12-941. PMID 2240918.
  8. ↑ Inouye, Sharon K.; Bogardus, Sidney T.; Charpentier, Peter A.; Leo-Summers, Linda; Acampora, Denise; Holford, Theodore R.; Cooney, Leo M. (1999-03-04). "A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients". New England Journal of Medicine. 340 (9): 669–676. doi:10.1056/NEJM199903043400901. ISSN 0028-4793. PMID 10053175. S2CID 18337230.
  9. ↑ "Sharon K. Inouye, M.D., M.P.H. | Hinda and Arthur Marcus Institute for Aging Research". www.marcusinstituteforaging.org. Retrieved 2022-09-13.
  10. ↑ Knox, Richard A. (August 17, 1999). "Delirium in hospitalization getting attention". Daily World. Retrieved October 18, 2021 – via newspapers.com.
  11. ↑ Strijbos, M. J.; Steunenberg, B.; Van Der Mast, R. C.; Inouye, S. K.; Schuurmans, M. J. (2013). "Design and methods of the Hospital Elder Life Program (HELP), a multicomponent targeted intervention to prevent delirium in hospitalized older patients: efficacy and cost-effectiveness in Dutch health care". BMC Geriatrics. 13: 78. doi:10.1186/1471-2318-13-78. PMC 3724594. PMID 23879226.
  12. ↑ "Sharon K. Inouye, MD, MPH". American Society for Clinical Investigation. Retrieved October 18, 2021.
  13. ↑ "Sharon K. Inouye, MD, MPH". Health and Aging Policy Fellows Program. Retrieved 2022-09-13.
  14. ↑ Hathaway, William (September 30, 2003). "PREVENTING DELIRIUM". Hartford Courant. Retrieved October 18, 2021.
  15. ↑ "Sharon Inouye Elected to Institute of Medicine in Washington". Rafu Shimpo. October 18, 2012. Retrieved October 18, 2021.
  16. ↑ "BIDMC researchers named among 'the most influential scientific minds'". Eurekalert. August 21, 2014. Retrieved October 18, 2021.
  17. ↑ "Dr. Inouye Awarded Federal Grant to Develop Worldwide Delirium Research Network". Hospital Elder Life Program. October 7, 2016. Retrieved October 18, 2021.
  18. ↑ "Dr. Inouye Earns GSA's M. Powell Lawton Award". Hospital Elder Life Program. December 5, 2016. Retrieved October 18, 2021.
  19. ↑ "Dr. Sharon Inouye Appointed to Prestigious National Fellowships". Hebrew Senior Life. January 27, 2017. Retrieved October 18, 2021.
  20. ↑ "Grantee in the News: Sharon Inouye selected as Next Avenue 2020 Influencer in Aging". American Federation for Aging Research. November 20, 2020. Retrieved October 18, 2021.
  21. ↑ "JAMA Network names new editor in chief of JAMA Internal Medicine". EurekAlert!. Retrieved 2023-03-02.
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