Music

• "Santa Maria" (Tatjana song), released 1995
• "Santa Maria" (Kenshi Yonezu song), released 2013
• "Santa Maria", 1976 song by Canadian rock band Trooper
• "Santa Maria", 1980 song by Guido & Maurizio De Angelis, a.k.a. Oliver Onions
• "Santa Maria", 1999 song by German band In Extremo
• "Santa Maria", 2001 song by Gotan Project
• "Santa Maria", 2001 song by The Frames
• "Santa María", a 2019 song by Bad Gyal featuring Busy Signal

Other media

• Santa Maria (operetta) by Oscar Hammerstein I
• Santa Maria, early title of the 2017 film Richie

Italy

Portugal

• Church of Santa Maria do Olival, a church in Tomar
• Jerónimos Monastery#Church of Santa Maria, a church in Lisbon

Spain

United States

• Iglesia San Isidro Labrador y Santa María de la Cabeza, Sabana Grande, Puerto Rico

Argentina

• Santa María, Catamarca
• Santa María Department (disambiguation), two departments in Argentina
• Santa María de Punilla
• Santa María, Misiones
• Santa María, Salta
• Santa María del Buen Ayre, old name of Buenos Aires
• Santa María Centro, Santa Fe
• Santa María Norte, Santa Fe

Brazil

• Santa Maria, Federal District
• Santa Maria, Rio Grande do Norte
• Santa Maria, Rio Grande do Sul
• Santa Maria das Barreiras, Pará
• Santa Maria da Boa Vista, Pernambuco
• Santa Maria do Cambucá, Pernambuco
• Santa Maria do Herval, Rio Grande do Sul
• Santa Maria de Itabira, Minas Gerais
• Santa Maria de Jetibá, Espírito Santo
• Santa Maria Madalena, Rio de Janeiro
• Santa Maria do Oeste, Paraná
• Santa Maria do Pará, Pará
• Santa Maria do Salto, Minas Gerais
• Santa Maria da Serra, São Paulo
• Santa Maria do Suaçuí, Minas Gerais
• Santa Maria do Tocantins, Tocantins
• Santa Maria da Vitória, Bahia

Cape Verde

• Santa Maria, Cape Verde

Chile

• Santa María, Chile

Colombia

• Santa María, Huila
• Santa María, Boyacá

El Salvador

• Santa María, Usulután

Guatemala

• Santa María Cahabón
• Santa María Chiquimula
• Santa María de Jesús
• Santa María Ixhuatán
• Santa María Visitación
• Santa María (volcano)

Italy

• Santa Maria Nuova, Marche, a comune in Marche
• Santa Maria di Castellabate, a town in Campania
• Santa Maria degli Angeli, Assisi

Malta

• Tigné Point, originally known as Punta di Santa Maria

Mexico

• Misión Santa María de los Ángeles, Baja California
• Santa María de los Ángeles, Jalisco
• Santa María del Oro, Durango
• Santa María del Oro, Nayarit
• Santa María del Río, San Luis Potosí
• Santa María, Oaxaca (disambiguation), several places

Panama

• Santa María District, Panama
• Santa María, Herrera

Paraguay

• Santa María, Paraguay, a city and district

Peru

• Santa María District, Huaura, a district in Huaura province
• Santa María del Mar (Peru), a district in Lima province

Philippines

• Santa Maria, Bulacan, a first-class urban municipality in the province of Bulacan
• Santa Maria, Davao Occidental
• Santa Maria, Ilocos Sur
• Santa Maria, Isabela
• Santa Maria, Laguna
• Santa Maria, Pangasinan
• Santa Maria, Romblon

Portugal

• Santa Maria (Tavira), a civil parish in the municipality of Tavira
• Sé, Santa Maria e Meixedo, a civil parish in the municipality of Bragança
• Cabo de Santa Maria (Faro), a cape south of Faro; the southernmost point of mainland Portugal
• Santa Maria Island, in the eastern group of the Azores

Romania

• Sântă Măria, a river in Sălaj County
• Sântă Măria, a village in the commune Sânmihaiu Almașului, Sălaj County

Spain

Switzerland

• Santa Maria in Calanca
• Santa Maria Val Müstair

United States

• Santa Maria, California
• Santa Maria, Texas
• Santa Maria Estate, U.S. Virgin Islands
• Santa Maria Valley AVA, California wine region

Vanuatu

• Gaua, formerly known as Santa Maria Island