1993 - 1997 : Debut and breakthrough

She emailed her photographs to Saawan Kumar. He signed her alongside Simran for Sanam Harjai which released in 1995. It was the first Indian film to be shot in New Zealand. This movie upon its release failed to make an impact at the box office. In 1997 she went on to star as the title lead Salma in the film Salma Pe Dil Aa Gaya opposite actor Ayub Khan. The same year she also made her debut there with Telugu movie Hello I Love You.

1998 - 2009 : Success in commercial movies

Starting 1998, she worked in films in the movie industry of South India. While in Bollywood she featured with actor Ayub Khan once again in the multi starrer Hafta Vasuli.

In the year 2000, she did a full time return to Bollywood and played the lead in Sabse Bada Beiman.^[3] She had several releases in 2002 like Kaaboo, Ab Ke Baras and Pyaasa. She played character with shades of grey in Kash Aap Hamare Hote (2003), Shikaar (2004) and Bullet: Ek Dhamaka (2005). She later signed projects like Ananth opposite Krushna Abhishek, Raj Sippy's Mr.Khujali, Ravi Sinha's Ghaav opposite Hyder Khan, The Real Cyanide, My Friend Ganesha 4 and producer Ved Gandhi's Aye Watan.^[4] All of these got shelved, remain unreleased and from some she opted out due to shooting date related issues. Saadhika played glamorous roles in Aggar (2007), Phir Tauba Tauba (2008) and Meri Padosan (2009). She also appeared in item numbers in several films like Choosoddaam Randi (2000), Satta (2003), Janam Janam Ke Saath (2007) and Wake Up India (2013). She has featured in album songs like Yeh Kaali Kaali Aakhen Remix sung by Aditya Narayan and worked with popular singer Daler Mehndi in his music video album Nabi Buba Nabi.

Saadhika has also featured in Bhojpuri cinema, including the films Pyar Ke Bandhan and Purab. She paired with Ravi Kishan in the films Dharam Veer, Paandav and Chandu Ki Chameli. She also worked in other Bhojpuri movies like Brijwa, Saat Saheliyan and Abhay Sinha's Janam Janam Ke Saath.^[5]

2010 - Present : Shift to realistic cinema

In 2010, she played the title role in the Punjabi movie Simran opposite actor Guggu Gill. This movie was based on the concept of loving the girl child. She was then seen opposite actor Naveen Vadde in Telugu movie Uncle Aunty Nandagopal. The following year she played a village belle in Hindi movie Rivaaz. Her other notable releases are Sai Ek Prerna (2011), Chand Ke Pare (2012), Saanwariya - Khatu Shyam Ji Ki Amar Gatha (2013) and Bhanwari Ka Jaal (2014). She played the role of a ghost in the movie Anhoni Saya which saw a digital release in 2016. Her most recent release was director Vicky Ranawat's Satya Sai Baba in January 2021 where she featured with actor Jackie Shroff and has singer Anup Jalota playing the titular role. This movie was released in four languages - English, Hindi, Telugu and Marathi. She is currently shooting for its sequel Satya Sai Baba 2 which is the directorial debut of singer Anup Jalota.

Television work

Throughout her career she kept balancing her commitments to movies with big budget Television serials. She played the role of a top model opposite actor Sanjay Kapoor in Karishma - The Miracles of Destiny and was seen in a traditional look in Jhilmil Sitaron Ka Aangan Hoga. She played the role of Indumati in the mythological Shobha Somnath Ki. She played lead role in 2009 Doordarshan serials Ek Din Achanak (TV series) and Panaah. She was seen as the title lead in Chandramukhi directed by Sunil Agnihotri and producer Dheeraj Kumar's family drama Hamari Bahu Tulsi. She started her own production company and during 2014 - 2016 she produced and acted as the lead in the Doordarshan prime time weekend show Janmon Ka Bandhan.

She is the winner of the 4th Annual Cinema Aajtak Achievers Awards (2020) under the Award category - Most Gorgeous Actress in Bollywood.