Patricia Zambryski
Other namesPatricia C. Zambryski O'Farrell
Alma materUniversity of Colorado
Scientific career
InstitutionsUniversity of California, Berkeley
ThesisThe Regulation of gene expression during bacteriophage T4 development (1974)

Patricia C. Zambryski is a plant and microbial scientist known for her work on Type IV secretion and cell-to-cell transport in plants. She is also professor emeritus at the University of California, Berkeley.[1]

She was an elected member of the National Academy of Sciences, the American Association for the Advancement of Science, and the American Society for Microbiology.

Education and career

Zambryski received her B.S. from McGill University in 1969, and earned a Ph.D. from the University of Colorado in 1974.[2][3]

Research

Zambryski is known for her work in the field of genetic engineering, specifically for her work with Agrobacterium tumefaciens, a bacterium she uses to track the molecular mechanisms that change plants and how plant cells communicate with each other.[3] She has examined the structure of plant cells that have been altered by Agrobacterium tumefaciens.[4] While working in Marc Van Montagu's lab, Zambryski determined how the Ti plasmid is identified by the bacterium, and she developed a vector that allowed the transfer of genetic material into a plant without altering the plant tissue.[5][6] This advance was used to inject novel genes into plants.[7] She has also examined plasmodesmata, which are the channels that reach across the spaces in plant cells.[8][9]

Selected publications

Awards and honors

In 2001 she was elected a member of the National Academy of Sciences[10] and a fellow of the American Society for Microbiology.[2] In 2010 she was elected a fellow of the American Association for the Advancement of Science.[2]

References

  1. "Patricia C. Zambryski". Plant & Microbial Biology | University of California, Berkeley. Retrieved 2022-05-02.
  2. 1 2 3 "Patricia C. Zambryski | Department of Plant & Microbial Biology | UC Berkeley". 2016-03-16. Archived from the original on 2016-03-16. Retrieved 2022-05-02.
  3. 1 2 Privalle, Laura S. (2017-03-08). Women in Sustainable Agriculture and Food Biotechnology: Key Advances and Perspectives on Emerging Topics. Springer. pp. 10–11. ISBN 978-3-319-52201-2.
  4. Zambryski, Patricia; Holsters, Marcelle; Kruger, Kelly; Depicker, Ann; Schell, Josef; Van Montagu, Marc; Goodman, Howard M. (1980-09-19). "Tumor DNA Structure in Plant Cells Transformed by A. tumefaciens". Science. 209 (4463): 1385–1391. Bibcode:1980Sci...209.1385Z. doi:10.1126/science.6251546. ISSN 0036-8075. PMID 6251546.
  5. Godwin, Ian D. (2019-01-18). Good Enough to Eat?: Next Generation GM Crops. Royal Society of Chemistry. ISBN 978-1-78801-681-0.
  6. Zambryski, P.; Joos, H.; Genetello, C.; Leemans, J.; Van Montagu, M.; Schell, J. (1983). "Ti plasmid vector for the introduction of DNA into plant cells without alteration of their normal regeneration capacity". The EMBO Journal. 2 (12): 2143–2150. doi:10.1002/j.1460-2075.1983.tb01715.x. PMC 555426. PMID 16453482.
  7. Schmeck, Harold M. (October 6, 1983). Gene-splicing of plants makes advance. Sarasota Herald-Tribune.
  8. Zambryski, Patricia; Crawford, Katrina (2000). "Plasmodesmata: Gatekeepers for Cell-to-Cell Transport of Developmental Signals in Plants". Annual Review of Cell and Developmental Biology. 16 (1): 393–421. doi:10.1146/annurev.cellbio.16.1.393. ISSN 1081-0706. PMID 11031242.
  9. Burch-Smith, Tessa M.; Zambryski, Patricia C. (2012-06-02). "Plasmodesmata Paradigm Shift: Regulation from Without Versus Within". Annual Review of Plant Biology. 63 (1): 239–260. doi:10.1146/annurev-arplant-042811-105453. ISSN 1543-5008. PMID 22136566.
  10. "Patricia C. Zambryski". www.nasonline.org. Retrieved 2022-05-02.
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