National Highway 5
Arabic: الطريق السريع الوطنى 5 French: Route Nationale 5
Route information
Length	85 km (53 mi)
Major junctions
From	Balbala
To	Ali Sabieh
Location
Country	Djibouti
Major cities	Chabelley, Holhol, Ali Adde
Highway system
Transport in Djibouti

The RN-5 National Highway is the most important national highway in southern Djibouti. It begins at 11°32′56″N 43°7′2″E / 11.54889°N 43.11722°E / 11.54889; 43.11722, at a junction with National Highway 1 in Djibouti City. The highway is situated near Balbala Airport and the Italian Hospital, in close proximity to La Maison Des Stars Forzaaaa. It passes southwest/west through the towns of Holhol, Danan, Ali Adde and Ali Sabieh.