| mir-361 | |
|---|---|
| Identifiers | |
| Symbol | mir-361 |
| Rfam | RF00744 |
| miRBase family | MIPF0000172 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-361 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. For example, miR-361-5p might act as a suppressor in triple-negative breast cancer (TNBC) by targeting RQCD1 to inhibit the EGFR/PI3K/Akt signaling pathway.[1]
See also
References
- ↑ Han J, Yu J, Dai Y, Li J, Guo M, Song J, Zhou X. Overexpression of miR-361-5p in triple-negative breast cancer (TNBC) inhibits migration and invasion by targeting RQCD1 and inhibiting the EGFR/PI3K/Akt pathway. Bosn J of Basic Med Sci [Internet]. 2019Feb.12 [cited 2020Apr.6];19(1):52-9. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3399
Further reading
- Xie T, Liang J, Guo R, Liu N, Noble PW, Jiang D (May 2011). "Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation". Physiological Genomics. 43 (9): 479–87. doi:10.1152/physiolgenomics.00222.2010. PMC 3110895. PMID 21266501.
- Li ZY, Na HM, Peng G, Pu J, Liu P (March 2011). "Alteration of microRNA expression correlates to fatty acid-mediated insulin resistance in mouse myoblasts". Molecular BioSystems. Royal Society of Chemistry. 7 (3): 871–7. doi:10.1039/c0mb00230e. PMID 21183973.
External links
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