Main

• Sohini Guha Roy^[4] as Tisham Sen (formerly Ghosh) (née Mitra) – Souradeep's wife, Shyam's former wife, Nilambar and Reshma's daughter (till his death)
• Soumya Mukherjee as Souradeep Sen aka Papan – Tisham's husband

Recurring

• Sabitri Chatterjee as Kamalini Sen – Souradeep's paternal grandmother, Raja and Paltu's mother, Bhombol's aunt
• Santu Mukherjee as Debshankar Sen aka Bhombol – Souradeep's elder paternal uncle, Protima's husband, Bubu's father, Samyo's father-in-law
• Rita Dutta Chakraborty as Protima Sen – Souradeep's elder aunt and foster mother, Bhombol's wife, Bubu's mother, Samyo's mother-in-law
• Kaushik Chakraborty as Rajdeep Sen aka Raja – Souradeep and Mitul's father, Souradeep's late mother and Malobika's husband, a businessman
• Tramila Bhattacharya as Malobika Sen – Raja's second wife, Souradeep and Mitul's stepmother. She is egocentric, diplomatic, dominating and quarrelsome in nature, and insults others.
• Biswanath Basu as Paltu Sen – Souradeep's younger paternal uncle who deeply cares for him and is like a friend to him. He is Kamalini's son and Annapurna's husband. He became a successful businessman.
• Tithi Bose as Annapurna Sen (née Dutta) – Paltu's wife, introduced as an innocent but outgoing comic character.
• Rajanya Mitra as Shreyashee Lahiri (née Sen) aka Bubu – Souradeep's elder paternal cousin sister, Bhombol-Protima's daughter, Samyo's wife.
• Suman Banerjee as Samyo Lahiri – Bubu's husband, Souradeep's elder brother-in-law and Bhombol-Protima's son-in-law.
• Soumi Banerjee as Shatabdi Sen aka Mitul – Souradeep's younger sister, Raja's daughter with his first wife.
• Nilankur Mukhopadhyay as Tamoghna Dutta aka Bublu – Kamalini's daughter's son, and Raja and Paltu's sororal nephew who lives with the Sen family. He is Souradeep's younger paternal cousin brother and Jhimli's love interest turned husband.

• Abhishek Chatterjee as Nilambar Mitra – Tisham's once estranged father. After his wife Reshma died, he passed upon Bablu the duty to raise Tisham and went to Kashi to live a spiritual life there. Later he helped Souradeep in rescuing Tisham and returned to Kolkata to support Tisham.
• Chandan Sen as Sameer Bose aka Bablu – Tisham's maternal uncle (who raised her), Mitali's husband, Jhimli's father. He is a school teacher.
• Laboni Sarkar as Mitali Bose – Tisham's aunt (Bablu's wife), Jhimli's mother. She is greedy, eccentric, finicky and barbaric by nature.
• Sonal Mishra as Jhimli Dutta (née Bose) – Tisham's younger cousin sister, Bablu-Mitali's daughter, Bublu's love interest turned wife

• Tathagata Mukherjee as Shyam Sundar Ghosh aka Shyam – Tisham's ex-husband. He was a drunkard and had a secret romantic/sexual relationship with his sister-in-law Kadambari. He developed a liking for Tisham, however, died in a road accident.
• Debolina Mukherjee as Kadambari Ghosh – Shyam's sister-in-law (his elder brother's wife). Her husband became mentally deranged and was admitted to a mental hospital after their wedding on seeing the growing proximity of his wife with his brother Shyam. Kadambari regulates Shyam's household and enticed him as well.
• Sreela Majumder as Shakuntala Ghosh – Shyam's mother, Tisham's former mother-in-law. She is kind-hearted and caring towards Tisham, but has been suppressed to give her views by her other family members.
• Sandip Dey as Bishnu Shankar Ghosh – Shyam's father, Tisham's former father-in-law. He is affluent but orthodox and uncultured.
• Chitra Sen as Bholadasi Dutta – Annapurna's paternal grandmother.
• Rajasree Bhowmick as Mishtu's mother