Combination of | |
---|---|
Isoniazid | Anti-tuberculosis medication |
Rifampicin | Anti-tuberculosis medication |
Clinical data | |
Trade names | IsonaRif, Rifamate, others |
ATC code | |
Identifiers | |
CAS Number | |
KEGG |
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis.[1] It is a fixed dose combination of isoniazid and rifampicin (rifampin).[1] It is used together with other antituberculosis medication.[1] It is taken by mouth.[1]
It is on the World Health Organization's List of Essential Medicines.[2]
Adverse effects and safety
Side effects are those of the underlying medications.[1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired.[3] More severe side effects include liver problems.[3] Use is generally not recommended in children.[1] It is unclear if use is safe in pregnancy.[4]
References
- 1 2 3 4 5 6 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 142. hdl:10665/44053. ISBN 9789241547659.
- ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- 1 2 "Isoniazid/rifampin Side Effects in Detail - Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
- ↑ "Isoniazid / rifampin Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
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