Idiopathic pneumonia syndrome
SpecialtyPulmonology

Idiopathic pneumonia syndrome is a set of pneumonia-like symptoms that occur with no sign of infection in the lung. Idiopathic pneumonia syndrome is a serious condition that can occur after a stem cell transplant. It occurs between 2.2 and 15 percent of hematopoietic stem cell transplants. The incubation period ranges between 4 and 106 days, but mostly is about 22 days from transplant.[1]

Symptoms

The symptoms are like pneumonia, and include fever, chills, coughing, and breathing problems. Lack of oxygen may also occur.[1]

Risk factors

Risk factors for IPS can be old age, graft vs host disease, multi organ failure, and multiple organ failure.[1]

Diagnosis

Treatment

Treatment is only supportive, with steroids showing no effect. The need for mechanical ventilation is indicative of a poor prognosis. Steroids are often used, though often without effect.[1]

References

  1. 1 2 3 4 Klein, Orly; Cooke, Kenneth (2015). "Idiopathic pneumonia syndrome following hematopoietic stem cell transplantation". Journal of Pediatric Intensive Care. 03 (3): 147–157. doi:10.3233/PIC-14098. PMC 6530755. PMID 31214462.

Public Domain This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.

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