Hyaluronoglucuronidase
Identifiers
EC no.3.2.1.36
CAS no.37288-34-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Hyaluronoglucuronidase (EC 3.2.1.36, hyaluronidase, glucuronoglucosaminoglycan hyaluronate lyase, orgelase) is an enzyme with systematic name hyaluronate 3-glycanohydrolase.[1][2] This enzyme catalyses the following chemical reaction

Random hydrolysis of (1→3)-linkages between β-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate

References

  1. Linker A, Meyer K, Hoffman P (April 1960). "The production of hyaluronate oligosaccharides by leech hyaluronidase and alkali". The Journal of Biological Chemistry. 235: 924–7. PMID 14417285.
  2. Meyer K, Hoffman P, Linker A (1960). "Hyaluronidases". In Boyer PD, Lardy H, Myrbaumlck K (eds.). The Enzymes. Vol. 4 (2nd ed.). New York: Academic Press. pp. 447–460.
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