Highwire (Hiw) is an E3 ubiquitin ligase protein associated with neuromuscular junction growth.[1] It is frequently studied in Drosophila melanogaster. Its known orthologs are PAM, RPM-1, and PHR-1.

References

  1. Bloom, Joseph A.; Bradley R. Miller; Joshua R. Sanes; Aaron DiAntonio (September 2007). "The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons". Genes & Development. 21 (20): 2593–2606. doi:10.1101/gad.1592107. PMC 2000324. PMID 17901218.
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