GUF1

GUF1
Identifiers
Aliases	GUF1, EF-4, GUF1 homolog, GTPase, EIEE40, EF4, GTP binding elongation factor DEE40
External IDs	OMIM: 617064 MGI: 2140726 HomoloGene: 6505 GeneCards: GUF1
Gene location (Human)
Chr.	Chromosome 4 (human)
End	44,700,928 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	69,733,316 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; biceps brachii; ; ganglionic eminence; ; Achilles tendon; ; rectum; ; cavity of mouth; ; amygdala; ; stromal cell of endometrium; ; dorsolateral prefrontal cortex; ; right ventricle;
	Top expressed in
	hand; ; otolith organ; ; utricle; ; lens; ; superior frontal gyrus; ; neural tube; ; proximal tubule; ; cerebellar cortex; ; esophagus; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; hydrolase activity; GTPase activity; ribosome binding;
Cellular component	mitochondrial inner membrane; membrane; mitochondrion; mitochondrial matrix;
Biological process	protein biosynthesis; positive regulation of translation;
	Sources:Amigo / QuickGO
Orthologs
	60558
	231279
	ENSG00000151806
	ENSMUSG00000029208
	Q8N442
	Q8C3X4
	NM_021927; NM_001345867; NM_001345868; NM_001345869
	NM_172711; NM_182768; NM_001310631
	NP_001332796; NP_001332797; NP_001332798; NP_068746
	NP_001297560; NP_766299
	Wikidata
View/Edit Human	View/Edit Mouse

GUF1 homolog, GTPase is a protein that in humans is encoded by the GUF1 gene. ^[5] It is the mitochondrial homolog of elongation factor 4.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000151806 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029208 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: GUF1 homolog, GTPase". Retrieved 2016-09-01.

Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.

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