Fumarate reductase is the enzyme that converts fumarate to succinate, and is important in microbial metabolism as a part of anaerobic respiration.[1] The catalyzed reaction is:

succinate + acceptor <=> fumarate + reduced acceptor

Fumarate reductases can be divided into two classes depending on the electron acceptor:

References

  1. 1 2 Tielens, A.G.; van Hellemond, J.J. (1998). "The electron transport chain in anearobically functioning eukaryotes". Biochim. Biophys. Acta. 1365: 71–78. doi:10.1016/s0005-2728(98)00045-0.
  2. Camarasa; et al. (2007). "Role in anaerobiosis of the isoenzymes for Saccharomyces cerevisiae fumarate reductase encoded by OSM1 and FRDS1". Yeast. 24: 391–401. doi:10.1002/yea.1467.
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