Enkephalinases are enzymes that degrade endogenous enkephalin opioid peptides. They include:
- Aminopeptidase N (APN)[1]
- Neutral endopeptidase (NEP)[1]
- Dipeptidyl peptidase 3 (DPP3)[1]
- Carboxypeptidase A6 (CPA6)[2]
- Leucyl/cystinyl aminopeptidase (LNPEP)
- Angiotensin-converting enzyme (ACE)[3]
See also
References
- 1 2 3 Thanawala V, Kadam VJ, Ghosh R (October 2008). "Enkephalinase inhibitors: potential agents for the management of pain". Current Drug Targets. 9 (10): 887–94. doi:10.2174/138945008785909356. PMID 18855623. Archived from the original on 2013-04-14.
- ↑ Lyons PJ, Callaway MB, Fricker LD (March 2008). "Characterization of carboxypeptidase A6, an extracellular matrix peptidase". The Journal of Biological Chemistry. 283 (11): 7054–63. doi:10.1074/jbc.M707680200. PMID 18178555.
- ↑ Benuck M, Berg MJ, Marks N (1982). "Separate metabolic pathways for Leu-enkephalin and Met-enkephalin-Arg(6)-Phe(7) degradation by rat striatal synaptosomal membranes". Neurochemistry International. 4 (5): 389–96. doi:10.1016/0197-0186(82)90081-X. PMID 20487892. S2CID 23138078.
| 3.4.11-19: Exopeptidase |
| ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3.4.21-25: Endopeptidase | |||||||||||||||
| 3.4.99: Unknown | |||||||||||||||
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.