Edward Malcolm Kosower (February 2, 1929 – April 7 2022) was an American-Israeli chemist.

Kosower was born in Brooklyn, New York on February 2, 1929 and attended high school at Stuyvesant, where he was a classmate of fellow chemist Andrew Streitwieser.[1]

He received his B.S. degree from the Massachusetts Institute of Technology in 1948 and Ph.D. from the University of California, Los Angeles in 1952 under the mentorship of Saul Winstein.[2] After postdoctoral research at Basel with Cyril Grob, and then at Harvard with Frank Westheimer, he began his independent career as assistant professor at Lehigh University (1954) and the University of Wisconsin (1956). In 1961, he moved to Stony Brook University as associate professor where he was later promoted to full professor. In 1972, he moved to Tel Aviv University, where he was named the Josef Kryss Professor of Biophysical Organic Chemistry in 1992.[3]

He was a Guggenheim Fellow from 1977 to 1978, and was a member of the American Association for the Advancement of Science.

He is best known for his earlier work in physical organic chemistry and later work in biophysical chemistry.[4] In particular, he developed the Z scale for solvent polarity based on the solvatochromic effect for zwitterionic dyes and investigated bimane dyes as fluorescent labels.[5][6]

Kosower is the author of an early textbook on physical organic chemistry, An Introduction to Physical Organic Chemistry (Wiley, 1968), and joined Streitwieser and Heathcock as coauthor of the 4th edition of their influential textbook, Introduction to Organic Chemistry (Macmillan, 1992).

References

  1. ↑ Tullo, Alexander H. "Roger Adams Award In Organic Chemistry | March 2, 2009 Issue - Vol. 87 Issue 9 | Chemical & Engineering News". cen.acs.org. Retrieved 2018-08-18.
  2. ↑ "Chemistry Tree - Edward M. Kosower Family Tree". academictree.org. Retrieved 2018-08-15.
  3. ↑ "Prof. Edward Kosower | Faculty of Exact Sciences Raymond & Beverly Sackler". en-exact-sciences.tau.ac.il. Retrieved 2018-08-15.
  4. ↑ Kosower, Edward (1997). "Rethinking Physical Organic Chemistry" (PDF). Pure Appl. Chem. 69 (2): 249–257. doi:10.1351/pac199769020249. S2CID 97625509.
  5. ↑ Kosower, Edward M. (July 1958). "The Effect of Solvent on Spectra. I. A New Empirical Measure of Solvent Polarity: Z-Values". Journal of the American Chemical Society. 80 (13): 3253–3260. doi:10.1021/ja01546a020. ISSN 0002-7863.
  6. ↑ Kosower, Nechama S.; Kosower, Edward M.; Newton, Gerald L.; Ranney, Helen M. (1979). "Bimane Fluorescent Labels: Labeling of Normal Human Red Cells under Physiological Conditions". Proceedings of the National Academy of Sciences of the United States of America. 76 (7): 3382–3386. Bibcode:1979PNAS...76.3382K. doi:10.1073/pnas.76.7.3382. JSTOR 69995. PMC 383829. PMID 291011.
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