ESCO1

ESCO1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MXE
Identifiers
Aliases	ESCO1, A930014I12Rik, CTF, ECO1, EFO1, ESO1, establishment of sister chromatid cohesion N-acetyltransferase 1
External IDs	OMIM: 609674 MGI: 1925055 HomoloGene: 62166 GeneCards: ESCO1
Gene location (Human)
Chr.	Chromosome 18 (human)
End	21,600,884 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	10,610,352 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; tibialis anterior muscle; ; secondary oocyte; ; Achilles tendon; ; deltoid muscle; ; palpebral conjunctiva; ; amniotic fluid; ; internal globus pallidus; ; thymus; ; testicle;
	Top expressed in
	saccule; ; secondary oocyte; ; otic placode; ; lacrimal gland; ; cumulus cell; ; olfactory epithelium; ; spermatocyte; ; blood; ; spleen; ; epithelium of stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; metal ion binding; N-acetyltransferase activity; zinc ion binding; peptide-lysine-N-acetyltransferase activity; identical protein binding; acetyltransferase activity;
Cellular component	chromatin; nucleus; nucleoplasm; chromosome;
Biological process	post-translational protein acetylation; cell cycle; sister chromatid cohesion; regulation of DNA replication; peptidyl-lysine acetylation;
	Sources:Amigo / QuickGO
Orthologs
	114799
	77805
	ENSG00000141446
	ENSMUSG00000024293
	Q5FWF5
	Q69Z69
	NM_052911
	NM_001081222; NM_144542
	NP_443143
	NP_001074691
	Wikidata
View/Edit Human	View/Edit Mouse

Establishment of sister chromatid cohesion N-acetyltransferase 1 is a protein that in humans is encoded by the ESCO1 gene.^[5]

Function

ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion.^[6]

PDBe-KB provides an overview of all the structure information available in the PDB for Human N-acetyltransferase ESCO1

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