Delayed pressure urticaria is known as one of the more painful subsets of physical urticaria due to formed hives being deep-seated and appearing after 4–6 hours.[1]

Causes

Due to the delayed appearance of wheals, plausible causes are hard to establish; the natural course and/or clinical pattern is variable and inconclusive.[1]

Treatment

It was noted that although antihistamines and anti-inflammatory drugs such as, colchicine, sulphasalazine, dapsone, and topical steroid are advocated for in the treatment of DPU, most if not all are unsatisfactory in relieving symptoms.[1] Even a second generation antihistamine, ketotifen, was unable to efficiently and satisfactorily relieve symptoms of DPU[2]

References

  1. 1 2 3 Dawn, G., M. Urcelay, A. Ah-Weng, S.m. O'neill, and W.s. Douglas. "Effect of High-dose Intravenous Immunoglobulin in Delayed Pressure Urticaria." Br J Dermatol British Journal of Dermatology 149.4 (2003): 836-40. Web.
  2. ↑ G. A. Vena, V. D'argento, N. Cassano,. "Sequential Therapy with Nimesulide and Ketotifen in Delayed Pressure Urticaria." Acta Dermato-Venereologica 78.4 (1998): 304-05. Web.


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