Sir

Christopher Evans

OBE ARCS FMedSci FREng FRSC FRSA FIBiol CCMI CChem
Born
Christopher Thomas Evans

(1957-11-29) 29 November 1957[1]
Port Talbot, Wales
NationalityBritish
Alma materImperial College London
University of Hull
OccupationBiotechnology entrepreneur & Scientist
TitleProfessor
SpouseLady Anne Evans

Sir Christopher Thomas Evans OBE ARCS FMedSci FREng FRSC FRSA FIBiol CCMI CChem (born 29 November 1957) is a Welsh professor, scientist and biotechnology entrepreneur. Evans is known for founding and co-founding numerous successful biotech companies in the United Kingdom.

Since the 1980s, Evans has launched and supported more than 50 companies in the biotechnology sector, including 20 listed on six different stock markets.[2] Many have specialised in their goal of creating unique products and medicines as well as clinical trials. These include an S-Ketoprofen anti-inflammatory pharmaceutical, single isomer chiral synthons for use in new anti-viral drugs, a single-isomer levobupivacaine for local anaesthesia, the pre-eminent rapid bioluminescent test for bacterial contamination, numerous enzymes and proteins for use in clinical diagnostic tests, as well as stem cell therapies, immunotherapeutics, oncology drugs and respiratory devices.

Early life

Evans was born in 1957, in Port Talbot, to Cyril and Jeanette (Cottey) Evans. He attended St Joseph's School in Port Talbot before studying microbiology at Imperial College London. He then obtained a PhD from the University of Hull and Porton Down, followed by a research fellowship at the University of Michigan.[1]

Career

Evans' first company, Enzymatix, was one of the earliest biotech companies in Europe.[3] Its early work involve the use of cabbages and eggs to mass-produce phospholipids which were used in surfactants to help premature babies breathe.[3] Evans was a co-founder of the biotech business Chiroscience, which was founded in 1991.[4] The company made a number of breakthroughs in the early 1990s. It developed an anesthetic known as Chirocaine,[5] and discovered Romosozumab, which was later acquired by Celltech.[4]

In 1992, Evans was the founder of Celsis, which was based in Cambridge, UK. It specialised in contamination detectors, which included a revolutionary test to detect E.coli in water.[6] Chiroscience became one of the UK's first biotech companies to go public in 1994, when it filed for its initial public offering.[4] Evans remained at the business for another couple of years and left prior to its merger with Celltech in 1999.[4]

Evans founded a number of ventures under the Merlin group. During the 1990s, Merlin focused on partnering with entrepreneurs to create new businesses, in a similar way to how seed funding is now used. Early investments were made in over 20 life science based companies. A £2.5 million investment was made in Cyclacel in 1997.[7]

In 1994, founded Toad, a vehicle technology company specialising in car security devices which went to be a publicly listed company.[8]

In 1997, Evans co-founded ReNeuron, a stem cell research company.[9] The company's research focused on treatments to reverse the effects of neurological diseases.[10]

In 1998, Evans founded Biovex, a company which specialised in the development of a genetically modified herpes virus which kills off cancer cells. The company was ultimately sold to Amgen in 2011 for $1 billion.[11] Later that year, Lord David Puttnam assembled a team of eight trustees for the National Endowment for Science, Technology and the Arts, which included Evans. This later became known as Nesta. It was awarded £200 million by the British government in the 1998 budget.[12] In 2000, ReNeuron was listed on the Alternative Investment Market in a £60 million listing.[10]

In 2004, Vectura a respiratory drug company founded by Evans was listed the Alternative Investment Market. In 2021, The Philip Morris Group made a successful bid of £1billion for the company.[13] Arakis Limited, one of the companies developed by Evans was sold to Sosei Co. Ltd for £106.5 million in 2005.[14]

Evans’ Excalibur Group sold Piramed, which developed treatments for cancer and autoimmune diseases to Roche in 2008 for £$175 million.[15]

In 2013, Evans founded Arthurian Life Sciences, which aimed to bring biotech investment into the Welsh economy.[16] A year later, it worked with the Welsh Government to create and build the Wales Life Sciences Investment Fund, a £100 million 50/50 joint venture life sciences investment fund created to attract business to Wales. The fund has invested in and provided grants to ReNeuron, in which Evans also invested.[17]

In 2015, Evans led the investment funding for Proton Partners International to create the UK's first network of centres offering proton beam therapy, a specialised form of radiotherapy. Proton Partners later became Rutherford Health and Evans remains a non-executive director.[18] In 2016, Evans founded and became deputy chairman of Arix Bioscience, a health and life sciences company investing in medical innovation. The company was listed on the London Stock Exchange with a market cap of £200m in 2017.[19]

In 2017, founded and became chairman of Ellipses Pharma, a company specialising in the development of new cancer drugs.[20]

In 2019, Evans created Excalibur Healthcare Services to specialise in international medical supplies, clinical research and development, diagnostics and testing. The company was formally incorporated in January 2020.[21]

In April 2020, Excalibur was at the forefront of the first phase of a clinical trial which could help diabetics that contract COVID-19.[22] The trial was arranged and structured by Evans. The second phase of the trial received £10 million in funding in August 2020.[23]

Awards

Evans holds 10 honorary professorships, 6 fellowships and a doctorate in sciences. He has been the author of more than 100 scientific publications and patents.[24]

In 1998, he became the youngest recipient of Society of Chemical Industry Centenary medal and was awarded the Henderson Memorial Medal. A year later in 1999, he received the Royal Society of Chemistry Interdisciplinary Medal.

Evans has twice been the recipient of "Cambridge Businessman of the Year" in 1996 and 1998.[25]

He was awarded the OBE in 1995 and knighted in 2001. He was appointed a Honorary Fellow[26] of the Royal Academy of Engineering[26] in 2005. In March of that year, he was appointed by Gordon Brown to the UK Stem Cell Initiative.[27] He made a £1 million loan to the British Labour Party during 2005, which became part of a wider police investigation into party donations,[28] but on 19 July 2007 the UK Crown Prosecution Service announced he was cleared of any wrongdoing.[29]

Personal life

Evans resides in the Cotswolds, and was listed in the Sunday Times Rich List 2020 in 583rd place with an estimated fortune of £208 million. He has a wife and four grown children.[30]

Philanthropy

In 2018, Evans launched the Evamore project, a musical collaboration inspired from the letters of First World War soldiers.[31]

The first release from the project, "One More Yard", was written by Evans and published in November 2018 to mark the centenary of Armistice Day. Sinéad O'Connor sang lead vocals on the track, with supporting vocals by Imelda May. Guitar was played by Ronnie Wood, with Nick Mason playing on drums, whilst instrumentation was provided by Brian Eno and spoken word excerpts recorded by actor Cillian Murphy.[32]

Proceeds from Evamore were donated to The Cancer Awareness Trust, a charity founded by Evans which aims to build ‘useful, reliable and easily understood information’ for use by individuals who have been diagnosed with cancer.

Evans founded The UK Stem Cell Foundation in 2005, a charity focused on funding stem cell research.[33]

References

  1. 1 2 Mosley, Charles, ed. (2003). Burke's Peerage, Baronetage & Knighthood (107 ed.). Burke's Peerage & Gentry. p. 1353. ISBN 0-9711966-2-1.
  2. ↑ "Speakers 2018 - Prof. Sir Christopher Evans, OBE, DSc, PhD". Vatican Conference.
  3. 1 2 Clarke, Jody (11 September 2009). "Sir Christopher Evans: How I turned a love of science into £150m". MoneyWeek.
  4. 1 2 3 4 Quested, Tony (7 June 2015). "Cream of life science entrepreneurs' first venture was selling doughnuts". Business Weekly. Cambridge, England: Q Communications. Retrieved 24 December 2018.
  5. ↑ "Focus Chiroscience". The Guardian. London, England: Guardian Newspapers, Ltd. 7 May 1999. Retrieved 24 December 2018.
  6. ↑ Taylor, Roger (17 April 1997). "Celsis launches test for E.coli contamination". Financial Times.
  7. ↑ Taylor, Roger (3 June 1997). "Merlin waves its Wand". Financial Times.
  8. ↑ Bowsher, Ed (21 May 2001). "Toad denies merger talks as founder bows out". CityWire.
  9. ↑ Hirschler, Ben (10 July 2015). "Cell therapy gets a boost as ReNeuron raises $105 million". Reuters.
  10. 1 2 Pfeffer, Sylvia (8 October 2000). "New Hope for Brain Diseases". Sunday Business.
  11. ↑ Timmerman, Luke (24 January 2011). "Amgen to Acquire BioVex for Up To $1B, to Obtain Cancer-Killing Virus Therapy". Xconomy.
  12. ↑ "Puttnam to head £200m 'board of British ideas'". The Times. 14 July 1998.
  13. ↑ Gretler, Corinne (1 October 2021). "Philip Morris Takeover of U.K. Drugmaker Vectura Near Completion". Bloomberg.
  14. ↑ "Japanese snap up Arakis". The Telegraph. 20 July 2005.
  15. ↑ Barry, Sion (March 2013). "Excalibur investors claim their slice of £36m – with more money still to come". WalesOnline.
  16. ↑ "Big Shot: Sir Chris Evans of Arthurian Life Sciences". The Times. 29 January 2013.
  17. ↑ "£50m investment fund to be examined". BBC News. 2 October 2013. Retrieved 25 January 2018.
  18. ↑ "Investors back £100m plan for UK proton-beam cancer centres". Financial Times. 3 April 2015.
  19. ↑ Adams, Ben (17 February 2017). "British investment firm Arix Bioscience hits £100M IPO target". Fierce Biotech.
  20. ↑ "Ellipses Announces Growth In Oncology Portfolio". PR Newswire.
  21. ↑ Bradshaw, Julia (21 February 2021). "Affordable British made Covid Drug could Slash mortality rates". Daily Telegraph.
  22. ↑ Ralph, Alex (22 April 2020). "Investors back potential drug for diabetic Covid-19 patients". The Times.
  23. ↑ Ralph, Alex (25 August 2020). "Investors Back potential drugs for diabetic Covid-19 patients". The Times.
  24. ↑ "Honorary graduates, 2000 to 2009". University of Bath.
  25. ↑ "Wizards has more magic up sleeve". Cambridge Evening News. 25 February 1997.
  26. 1 2 "List of Fellows". Archived from the original on 8 June 2016. Retrieved 28 October 2014.
  27. ↑ Webb, Tim (20 March 2005). "Laboratory to the world: the UK's big push on stem cells". The Independent.
  28. ↑ "Profile: Sir Christopher Evans". 21 September 2006. Retrieved 25 January 2018 – via news.bbc.co.uk.
  29. ↑ "Q&A: Cash-for-honours". 20 July 2007. Retrieved 16 December 2020.
  30. ↑ Wood, Vincent (1 August 2018). "Biotech tycoon Sir Chris Evans puts up reward to find thieves who took £1m jewellery". The Times. ISSN 0140-0460. Retrieved 1 August 2018.
  31. ↑ Kelly, Emma (14 November 2018). "Imelda May and Nick Mason join star-studded track to commemorate Armistice and raise cancer awareness". Metro (newspaper).
  32. ↑ Barry, Sion (24 October 2018). "Some of the biggest names in music have come together to make a charity album for cancer, thanks to a Welsh businessman". Media Wales.
  33. ↑ "Call for £100m UK stem cell fund". BBC. 8 February 2005. Retrieved 11 January 2023.
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