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Beta-defensin 3 is a protein that in humans is encoded by the DEFB3 gene.[1]
HBD-3 was first isolated from human lesional psoriatic scales. RT-PCR showed HBD-3 to be expressed highly in skin, trachea, tongue and tonsils, with lower levels found salivary glands, uterus, kidney, bone marrow, thymus, colon, stomach, adenoid, pharynx, and larynx.[2]
References
- ↑ Bensch KW, Raida M, Mägert HJ, Schulz-Knappe P, Forssmann WG (July 1995). "hBD-1: a novel beta-defensin from human plasma". FEBS Letters. 368 (2): 331–5. doi:10.1016/0014-5793(95)00687-5. PMID 7628632. S2CID 84766207.
- ↑ Dhople V, Krukemeyer A, Ramamoorthy A (September 2006). "The human beta-defensin-3, an antibacterial peptide with multiple biological functions". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758 (9): 1499–512. doi:10.1016/j.bbamem.2006.07.007. PMID 16978580. S2CID 36461159.
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