Doubles
2021 Winston-Salem Open
Champions	Marcelo Arévalo Matwé Middelkoop
Runners-up	Ivan Dodig Austin Krajicek
Score	6–7(5–7), 7–5, [10–6]

Łukasz Kubot and Marcelo Melo were the reigning champions from when the tournament was last held in 2019, but lost in the semifinals to Ivan Dodig and Austin Krajicek.

Marcelo Arévalo and Matwé Middelkoop won the title, defeating Dodig and Krajicek in the final, 6–7^(5–7), 7–5, [10–6].

Seeds

Draw

Draw

	First round							Quarterfinals							Semifinals							Final
	1	Ł Kubot M Melo	6	6
	WC	S Banthia M Thomson	2	4				1	Ł Kubot M Melo	1	6	[10]
		A Behar G Escobar	6	65	[5]				K Skupski N Skupski	6	2	[7]
		K Skupski N Skupski	4	77	[10]										1	Ł Kubot M Melo	3	4
	3	R Klaasen B McLachlan	3	6	[4]											I Dodig A Krajicek	6	6
		M Daniell M Demoliner	6	4	[10]				M Daniell M Demoliner	68	2
		I Dodig A Krajicek	77	6					I Dodig A Krajicek	710	6
	WC	N Monroe J Withrow	64	4																			I Dodig A Krajicek	77	5	[6]
		A Golubev A Mies	2	7	[9]																		M Arévalo M Middelkoop	65	7	[10]
		M Arévalo M Middelkoop	6	5	[11]				M Arévalo M Middelkoop	3	78	[10]
		L Saville J-P Smith	6	6					L Saville J-P Smith	6	66	[7]
	4	S Bolelli M González	3	4												M Arévalo M Middelkoop	6	6
		O Marach P Oswald	77	5	[10]											O Marach P Oswald	3	3
		S Gillé J Vliegen	64	7	[4]				O Marach P Oswald	w/o
		T Brkić N Ćaćić	4	1				2	N Mahut F Martin
	2	N Mahut F Martin	6	6

References

External links

• Main Draw