pyrrolobenzodiazepine

English

Etymology

pyrrol + -o- + benzo- + di- + azepine

Noun

pyrrolobenzodiazepine (plural pyrrolobenzodiazepines)

  1. (pharmacology) A class of compounds with antibiotic and anti-tumor properties.
    • 2015 August 19, Maria Mellinas-Gomez et al., “Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours”, in BMC Veterinary Research, volume 11, →DOI:
      SG2000 (SJG-136, NSC694501) is a rationally designed pyrrolobenzodiazepine dimer which interacts sequence selectively in the minor groove of DNA.
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