isatin

English

Structure diagram of isatin

Noun

isatin (countable and uncountable, plural isatins)

  1. (organic chemistry) The indole derivative 1H-indole-2,3-dione, used in the synthesis of dyes.
    • 1993, Vivette Glover, Merton Sandler, “Tribulin and Isatin: An Update”, in Hajime Yasuhara, S. H. Parvez, editors, Monoamine Oxidase: Basic And Clinical Aspects, page 68:
      This finding suggests that the gut flora (absent, of course, in germ free animals) are responsible for the generation of most urinary isatin, but that the tissue material derives from a different source.
    • 2007, Shang-Tian Yang, Xiaoguang Liu, Yali Zhang, “Chapter 4: Metabolic Engineering - Applications, Methods, and Challenges”, in Shang-Tian Yang, editor, Bioprocessing for Value-Added Products from Renewable Resources, page 81:
      One problem in large scale denim dyeing processes using biologically produced indigo is the undesirable red cast caused by indirubin, which is a structural isomer of indigo formed from indoxyl and isatin, a byproduct of the spontaneous oxidation reaction that converts indoxyl to indigo.
    • 2014, Kiran Gangarapu, Development of Isatin as CNS Agents: Anticonvulsant activity, Anchor Academic Publishing, page 7:
      Isatin reacts with formaldehyde and a variety of amines in the Mannich reaction to give their respective bases (10), in the absence of an amine, isatin and substituted isatin with formaldehyde give hydroxymethyl isatins (11).

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