The 4-Toluene Sulfonate Uptake Permease (TSUP) family (TC# 2.A.102) is also referred to as the TauE/SafE/YfcA/DUF81 Family.

Although its members have not been rigorously characterized, evidence is available that at least some members function in the transport of Sulfur containing Organic compounds. These include 4-toluene sulfonate which may be transported by the TsaS of Cupriavidus necator (TC# 2.A.102.1.1), sulfolactate which may be exported by the TauE protein of Cupriavidus necator (TC# 2.A.102.2.1) [1][2] and sulfoacetate which may be exported by the SafE1 protein of Neptuniibacter caesariensis (TC# 2.A.102.2.2).[3] Another member of the TSUP family, TsaS of Comamonas testosteroni, has been reported to function in the uptake of 4-toluene sulfonate.[4] None of these functional assignments can be considered to be certain.[5]

References

  1. ↑ Weinitschke, S; Denger, K; Cook, AM; Smits, TH (September 2007). "The DUF81 protein TauE in Cupriavidus necator H16, a sulfite exporter in the metabolism of C2 sulfonates". Microbiology. 153 (9): 3055–60. doi:10.1099/mic.0.2007/009845-0. PMID 17768248.
  2. ↑ Mayer, J; Denger, K; Hollemeyer, K; Schleheck, D; Cook, AM (November 2012). "(R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with excretion of 3-sulfolactate: a patchwork pathway". Archives of Microbiology (Submitted manuscript). 194 (11): 949–57. Bibcode:2012ArMic.194..949M. doi:10.1007/s00203-012-0825-y. PMID 22797525. S2CID 18532277.
  3. ↑ Krejcík, Z; Denger, K; Weinitschke, S; Hollemeyer, K; Paces, V; Cook, AM; Smits, TH (August 2008). "Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase". Archives of Microbiology (Submitted manuscript). 190 (2): 159–68. Bibcode:2008ArMic.190..159K. doi:10.1007/s00203-008-0386-2. PMID 18506422. S2CID 16756687.
  4. ↑ Mampel, J; Maier, E; Tralau, T; Ruff, J; Benz, R; Cook, AM (October 1, 2004). "A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2". Biochemical Journal. 383 (1): 91–9. doi:10.1042/bj20040652. PMC 1134047. PMID 15176949.
  5. ↑ Saier, MH Jr. "2.A.102. The 4-Toluene Sulfonate Uptake Permease (TSUP) Family". Transporter Classification Database. Saier Lab Bioinformatics Group.

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.