Spada is the Italian word for sword and a surname of Italian origin. It may refer to:

People

• Bernardino Spada (1594–1661), Italian Roman Catholic cardinal; patron of the arts
• Constanza Spada, stage name of Italian actress, singer and model Laura Troschel (1944–2016)
• Ercole Spada (born 1937), Italian automobile designer
• Fabrizio Spada (1643–1717), Italian Roman Catholic cardinal and Cardinal Secretary of State
• Giambattista Spada (1597–1675), Italian Roman Catholic cardinal
• Giovanni Jacopo Spada (1680–1774), Italian naturalist and pioneering geologist
• Giuliana Spada (born 1971), Italian retired heptathlete
• Ilaria Spada (born 1981), Italian actress and showgirl
• János Spáda (1877–1913), Hungarian architect also known as John Spada
• Katiuscia Spada (born 1981), Italian sport shooter
• Leonello Spada (1576–1622), Italian painter of the Baroque era
• Lorenzo Spada (died 1544), Italian Roman Catholic prelate and Bishop of Calvi Risorta
• Marcantonio M. Spada (born 1970), Italian-British psychologist
• Marcello Spada (1905–1995), Italian film actor
• Michelangelo Spada (fl. 1730), Italian painter
• Mirko Spada (born 1969), Swiss decathlete
• Patricio Spada (born 1993), Argentine footballer
• Robert Spada (fl. 1999–2008), American politician
• Romi Spada, Swiss bobsledder in the early 1950s

Other uses

• Palazzo Spada, a historic palace in Rome
  • Galleria Spada, a museum in the Palazzo Spada
• Palazzo Spada (Terni), a palace the city of Terni, Italy
• Honda VT250 motorcycle, frequently referred to as the Spada
• Spada Codatronca, Italian-built supercar by Spada Vetture Sport
• Cape Spada, the north-western extremity of Crete - see Battle of Cape Spada (World War II)
• Spada Lake, the reservoir of Culmback Dam, Washington state, United States
• Beatmania IIDX 21: Spada, a music video game
• Spada, a character from Japanese tokusatsu series Uchu Sentai Kyuranger
• Cardinal Cesare Spada, a minor character in the novel The Count of Monte Cristo whose fortune is found by protagonist Edmond Dantès