Sanford is a surname. Notable people with the surname include:
- Adam Sanford, Dominican cricketer
- Agnes Sanford, American Christian writer
- Arlene Sanford, American film and television director
- Chance Sanford, American baseball player
- Charles S. Sanford Jr., American businessman
- Chris Sanford (born 1968), American retired mixed martial artist
- Claudius Sanford, Dominican politician in the House of Assembly of Dominica
- Curtis Sanford, Canadian ice hockey goaltender
- Donald Sanford, American-Israeli Olympic sprinter
- Edmund Sanford, American psychologist
- Edward Sanford (disambiguation), multiple people
- Elias B. Sanford (1843–1932), American clergyman
- Eva Matthews Sanford (1894–1954), American Medieval and Classical Scholar
- Fred Sanford, American baseball player
- Fred Sanford, American musician
- Garwin Sanford, Canadian actor
- Henry Shelton Sanford, American diplomat and businessman, founder of the city of Sanford, Florida.
- Isabel Sanford, American actress and comedian
- Jack Sanford (1917–2005), American baseball player (first baseman)
- Jack Sanford (1929–2000), American baseball player (pitcher)
- James Sanford (disambiguation), multiple people
- John A. Sanford (1929–2005), also known as Jack, American Jungian psychoanalyst and Episcopal priest
- John C. Sanford (born 1950), American plant geneticist and advocate of intelligent design and young earth creationism
- John E. Sanford (died 1907), U.S. politician in Massachusetts
- John Elroy Sanford, birth name of American comedian Redd Foxx
- John F. A. Sanford, one party to the U.S. Supreme Court case of Dred Scott v. Sandford [sic]
- John Langton Sanford (1824–1877), English historical writer
- John Sanford (author) (1904–2003), American author and screenwriter, born Julian Lawrence Shapiro
- John Sanford (governor) (1605–1653), founder of Portsmouth, Rhode Island, USA
- John Sanford (1803) (1803–1857), U.S. Representative from New York
- John Sanford (1851) (1851–1939), U.S. Representative from New York
- John W. A. Sanford (1798–1870), U.S. Representative from Georgia
- Katherine Sanford (1915–2005), American cancer biologist
- Kiki Sanford, American neurophysiologist and science communicator
- Leonard Cutler Sanford (1868–1950), American surgeon and ornithologist
- Lillias Rumsey Sanford, American school founder
- Linda Sanford (born 1953), American technology executive
- Louis Childs Sanford, American Episcopal bishop
- Lucius Sanford, American American football player
- Maria L. Sanford, American educator
- Margaret Rose Sanford (1918–2006), First Lady of North Carolina
- Mark Sanford (born 1960), American South Carolina politician
- Mike Sanford, American college football coach
- Mike Sanford Jr., American football coach
- Mitchell Sanford (1799–1861), New York politician
- Nathan Sanford (1777–1838), New York politician, US Senator
- Nehemiah Curtis Sanford, American industrialist and politician
- Reuben Sanford (1780–1855), New York politician
- Richard K. Sanford (1822–1895), New York politician
- Roscoe Frank Sanford, American astronomer
- Scott Sanford (born 1963), American politician, accountant, and Baptist clergyman
- T. Denny Sanford, American businessman and philanthropist
- Taylor Sanford, American baseball player, coach, and college athletics administrator
- Terry Sanford (1917–1998), American governor and senator from North Carolina
- Vincent Sanford (born 1990), American basketball player
- William Ayshford Sanford (1818–1902), naturalist and Colonial Secretary of Western Australia
- William Eli Sanford, Canadian businessman, philanthropist, and politician
- Winifred Sanford (1890–1983), American writer
- Zach Sanford (born 1994), American ice hockey player
Fictional characters
- Fred G. Sanford, of the TV series Sanford and Son
- Lamont Sanford, of the TV series Sanford and Son, portrayed by Demond Wilson
See also
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