St. Lucie may refer to:
- St. Lucie County, Florida
- St. Lucie County, Florida (1844-1855)
- St. Lucie Inlet, Florida
- St. Lucie Mets, minor league baseball team
- St. Lucie Nuclear Power Plant, Florida
- St. Lucie River, Florida
- St. Lucie Village, Florida
- St. Lucie County, Florida, Florida county founded in 1905
- St. Lucie Village, Florida, Florida town
See also
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