In public transport, Route 4 may refer to:
- Route 4 (MTA Maryland), a bus route in the suburbs of Baltimore, Maryland
- Barcelona Metro line 4
- NWFB Route 4, a bus route in Hong Kong
- London Buses route 4
- Line 4 (Madrid Metro)
- Line 4 Yellow (Montreal Metro)
- 4 (New York City Subway service), a subway line in New York City
- Shanghai Metro Line 4
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