Piko may refer to:
- PIKO, a model train manufacturer
- Street name for Methamphetamine in many Central and Eastern European countries
- Piko Interactive, an American game developer and publisher.
- Piko (singer) (b. 1988), a Japanese pop singer
- Piko (Filipino game), a Filipino children's game similar to hopscotch
- Piko, renamed Penny in English dubbing, a character from the anime Stitch!
- Piko (wrestler), a Japanese professional wrestler
See also
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