1980s

In 1981, she joined Roger Louret, whom she had met in Paris, in Monclar, with his theatre company, Les Baladins en Agenais. Notable people that she met there include Elie Semoun and Annie Grégorio. In 1983, she returned to Paris with Annie Grégorio to work at the Petit Théâtre de Bouvard., where she also met Didier Bénureau. She came up against the authoritarian methods of Philippe Bouvard, but, even so, he gave her a part in a play he had written, Double Foyer. Following that, she played in a role co-written with Didier Bénureau, Maman ou Donne-moi ton linge, je fais une machine, (Mother, or, Give me your laundry, I am washing a load), in 1986, in Avignon, and in 1987 in Paris, at the Théâtre de Dix heures. The play was later shown in Monclar at the Théâtre de Poche. She became known to the wider public, towards the end of the 1980s through a television programme called La Classe, broadcast by FR3 (which became France 3). Muriel Robin met and became good friends with Pierre Palmade. They created her first one-woman-show together, Les majorettes se cachent pour mourir, in 1988, directed by Roger Louret. This programme was a success and pushed Robin into the limelight.

1990s

During the 1990s, Robin appeared in plays including Tout m’Enerve, Bedos-Robin a collaboration with Roger Louret, Feu la Ma La Mère, and On Purge Bébé. She also presented on radio, on Europe 1, with her programme, Tout Robin. In 1997, she obtained her first role in cinema, replacing Valérie Lemercier in Les Couloirs du temps : Les Visiteurs 2 by Jean-Marie Poiré. The same year she wrote and directed with Pierre Palmade in the play, Ils s'aiment,(They Love Each Other) played by Pierre Palmade and Michèle Laroque, which was a success and received a nomination for the Molière for the Best One-Man-Show or Sketch Show.

2000s

In May, 2000, she announced that she would finish with the genre of the one-woman-show and concentrate on her profession as a comedian, but also that year, took her first big role in cinema in the eponymous role of Marie-Line, by Medhi Charef. Other roles on stage and screen followed, in the following years.

Charity work

Between 1992 and 2007, Muriel Robin was active in supporting concerts by the Enfoirés given for "the Restos du Cœur" created by Coluche and of which she became a sponsor until 2007. In 2001 she became equally involved with the journalist Marine Jacquemin in "La Chaine de l’Espoir" (The Chain of Hope) organised by the French Medical Institute for "L'Enfant de Kaboul" (The child of Kabul), in Afghanistan. This hospital opened in 2005.

In 2022 French actors cut their hair in support of women in Iran. The protesters included Marion Cotillard and Juliette Binoche, as well as Isabelle Adjani, Charlotte Gainsbourg, Jane Birkin and Muriel Robin.^[5]