Muradyan (Armenian: Մուրադյան) is a surname originating in Armenia. It may also refer to:
- Badal Muradyan (1915–1991), Prime Minister of Armenian SSR (1966–1972)
- Igor Muradyan (1957–2018), Armenian political activist
- Karen Muradyan (born 1992), Armenian footballer
- Nina Muradyan (born 1954), Soviet volleyball player
- Rudolf Muradyan (born 1936), Soviet and Armenian theoretical physicist
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