Michael Kane may refer to:
- Mike Kane (born 1969), British Labour MP
- Michael F. Kane (born 1967), member of the Massachusetts House of Representatives
- Michael N. Kane (1851–1924), American lawyer, judge, and politician from New York.
- Michael Kane (actor), Canadian actor in The Gunfighters
- Michael Kane (writer), American writer and journalist for several publications
- Michael Kane, the protagonist of the Old Mars novels by Michael Moorcock
See also
- Michael Cain (born 1966), pianist and composer
- Michael Caine (born 1933), actor
- Michael Caines (born 1969), chef
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