The McKesson Corporation is a corporation specializing in the distribution of health care systems, medical supplies and pharmaceutical products.

McKesson may also refer to:

• The McKesson & Robbins scandal (1938), a business and accounting scandal in the early 20th century involving a predecessor of the McKesson Corporation
• Mckesson v. Doe, a decision by the U.S. Supreme Court
• McKesson Information Solutions, Inc. v. Bridge Medical, Inc., a 2007 patent case on the doctrine of inequitable conduct
• McKesson Plaza, an office skyscraper located in San Francisco's Financial District
• Malcolm McKesson (1909–1999), American artist known for his ballpoint pen drawings and erotic fiction
• DeRay Mckesson (b. 1985), American civil rights activist