Jewel box or Jewel Box may refer to:

• Jewelry box, a container for gemstones

Places or architecture

• Jewel Box (St. Louis), listed on the NRHP in Missouri
• Jewel Boxes, a name for eight banks designed by architect Louis Sullivan
• Jewel Box Park, a type of baseball park

Star cluster

• Jewel Box (star cluster) (NGC 4755), a star cluster in Crux

Music

• "Jewel Box", a track on Jeff Buckley's Sketches for My Sweetheart the Drunk
• The Jewel Box, a 1991 pasticcio opera with music by Wolfgang Amadeus Mozart and libretto by Paul Griffiths
• Elton: Jewel Box, an 8-disc compilation featuring rare songs by Elton John

Biology

• Chamidae, a family of bivalves known as the jewelboxes
• Jewel-box pea crab, a common name for the Gemmotheres chamae crab

Other

• Jewelbox (video game), a tetris-style arcade game for the Mac
• Jewel case, Jewel box or Super Jewel Box, types of Optical disc packaging
• Tomb of I'timād-ud-Daulah, at Agra is known as Jewel Box for its intricate parchin kari work