James or Jim Blake may refer to:

Entertainment

• James W. Blake (1862–1935), American lyricist
• James Blake (pianist) (1922–1979), British-American jazz musician
• James Carlos Blake (born 1947), American writer, winner of Los Angeles Times Book Prize for fiction, 1997
• James Blake (musician) (born 1988), British singer-songwriter
  • James Blake (album), self-titled debut album
• Eubie Blake (James Hubert Blake, 1887–1983), American musician
• Jim Blake, character in the film Across the Plains (1928)

Politics

• James H. Blake (1768–1819), American politician, mayor of Washington, D.C.
• Jim Blake (Australian politician) (1921–2010), member of the Queensland Legislative Assembly
• James B. Blake (1827–1870), American politician, mayor of Worcester, Massachusetts

Other uses

• James "Spanish" Blake (died 1635), Irish Nine Years' War figure
• James Henry Blake (1808–1874), Boston Police Marshal in 1840
• James Vila Blake (1842–1925), American Unitarian minister, essayist, playwright and hymn writer and poet
• James F. Blake (1912–2002), American bus driver defied by Rosa Parks
• Ronald James Blake (born 1934), aka James Blake, British civil engineer in Hong Kong, CEO of KCRC
• James Blake (tennis) (born 1979), American professional tennis player
• James Blake House, oldest house in Boston