Jaafari may refer to:
- Jaʽfari jurisprudence, the Juridical school followed by Twelver and Nizari Shi'a, named after Ja'far al-Sadiq
- Al-Ja'fari, a surname commonly associated with descendants of Ja'far al-Sadiq, including notable people with the surname
See also
- Ja'far al-Sadiq (702-765), holy Sixth Imam for the majority of Shia Muslims
- Jaʽfar, a given name common among Shia Muslims
- Twelver Shi’ism, the largest branch of Shia Islam
- Nizari Isma'ilism, the second largest branch of Shia Islam
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