Boss/acting boss

• Giuseppe "the Clutch Hand" Morello – boss (1890s–1909)
• Nicholas "Nick" Morello – boss (1909–1916) killed in 1916
• Vincenzo "Vincent" Terranova – boss (1916–1920)
• Giuseppe "Joe the boss" Masseria – boss (1920–1931)
• Charlie "Lucky" Luciano – boss (1931–1946)
• Frank "The Prime Minister" Costello – acting boss (1936–1945), boss (1946–1957)
• "Don" Vito Genovese – underboss (1931–1936), boss (1957–1969)
• Anthony "Tony Bender" Strollo – acting boss (1959–1962)
• Thomas "Tommy Ryan" Eboli – acting boss (1962–1965)
• Frank Tieri – front boss (circa 1972–1981)
• Philip Lombardo – boss (1969–1981)
• Anthony "Fat Tony" Salerno – front boss (1981–1987)
• Vincent "Chin" Gigante – underboss (1981–1987), boss (1981–2005)
• Liborio Bellomo – acting boss (1990–1992), street boss (1992–1996), boss (2010–present)
• Dominick "Quiet Dom" Cirillo – acting boss (1997–1998)
• Matthew "Matty The Horse" Ianniello – acting boss (1997–2005)
• Mario Gigante – street boss (2006–2007)
• Daniel Leo (mobster) – acting boss (2005–2008)

Underboss/consigliere

• Willie Moretti – underboss, capo
• Venero Mangano – underboss, capo
• Gerardo Catena – underboss, capo
• Saverio Santora – underboss, capo
• Michele Miranda – consigliere
• Louis Manna – consigliere
• James Ida – consigliere
• Lawrence Dentico – consigliere

Capo/soldier/associate

• Joe Adonis – capo
• Adolfo Bruno - capo
• Peter DeFeo – capo
• Anthony Provenzano – capo
• Anthony Strollo – capo
• Tino Fiumara – capo
• Vincent Alo – capo
• Anthony Carfano – capo
• Michael Coppola – capo
• John Ardito – capo
• Angelo DeCarlo – capo
• Vincent Cafaro – soldier, government informant (1986)
• Joseph Lanza – soldier (circa 1920s–1968)
• Joseph Valachi – soldier, government informant
• Carmine Romano – soldier

Boss/acting boss

• Salvatore "Toto" D'Aquila boss (1916–1928)
• Manfredi "Al" Mineo – boss (1928–1930)
• Frank Scalice – boss (1930–1931)
• Vincent Mangano – boss (1931–1951)
• Albert "The Lord High Executioner" Anastasia – boss (1951–1957), underboss (1931–1951)
• Carlo "Don Carlo" Gambino – boss (1957–1976), underboss (1957)
• Paul "Big Paulie" Castellano – boss (1976–1985)
• John "The Teflon Don" Gotti – boss (1985–2002)
• Junior Gotti – acting boss (1992–1996, 1997–1999)
• Peter Gotti – boss (2002–2011); acting boss (1999–2002)
• Arnold Squitieri – acting boss (2002–2005)
• Jackie D'Amico – acting boss (2005)
• Nicholas Corozzo – acting boss (2005–2008)
• Jackie D'Amico – street boss (2008–2011)
• Domenico Cefalu – boss (2011–present)
• Frank Cali - acting boss (2015–2019)

Underboss/consigliere/capo

• Aniello "Mr. Niel" Dellacroce – underboss (1965–1985)
• Frank DeCicco – underboss (1985–1986)
• Joseph Armone – underboss (1986–1990), consigliere (1990–1992)
• Salvatore "Sammy the Bull" Gravano – underboss (1990–1992), consigliere (1987–1990)- Became a government informant
• Thomas Bilotti – underboss (1985)
• Frank Locascio – acting underboss (1986–1990), acting consigliere (1990–1992)
• Arnold Squitieri – acting boss (2002–2005)
• Joseph N. Gallo – consigliere (1957–1986)
• Joseph Corozzo – consigliere (1992–present)
• Carmine Lombardozzi – capo
• Anthony Gaggi – capo
• Michael DiLeonardo – capo
• Anthony Scotto – capo
• Anthony Ciccone – capo
• Carmine Fatico – capo
• Angelo "Quack Quack" Ruggiero – capo
• Nicholas Corozzo – capo
• Gene Gotti – capo
• John A. Gotti – capo
• Richard V. Gotti – capo
• Ronnie Trucchio – capo
• Salvatore Scala – capo
• Salvatore LoCascio – capo
• Louis Ricco – capo
• James Squillante – capo
• James Failla – capo
• Thomas Gambino – capo
• Stephen Grammauta – capo
• George Remini – capo
• Jackie D'Amico – capo
• Leonard DiMaria – capo
• George DeCicco – capo
• Thomas Cacciopoli – capo
• Robert "DB" DiBernardo – capo
• John Gambino – capo
• Pasquale Conte – capo

Soldier/associate

• Roy DeMeo – soldier
• Joseph Paruta – soldier
• Joseph Vollaro – associate
• Dominick Montiglio – associate

Boss/acting boss

• Gaetano Reina – boss (1916–1930)
• Joseph Pinzolo – boss (1930)
• Tommaso Gagliano – boss (1930–1951)
• Gaetano "Tommy Brown" Lucchese – boss (1951–1967); underboss (1931–1951)
• Carmine Tramunti – boss (1967–1973)
• Anthony Corallo – boss (1973–1986)
• Vic Amuso – boss (1987–2012)
• Alphonse D'Arco – acting boss (1990–1991); capo (1988–1991)
• Joseph DeFede – acting boss (1994–1998)
• Steven Crea – acting boss (1998–2001); underboss (1994–present)
• Matthew Madonna – acting boss (2009–2017)

Underboss/consigliere/capo/soldier/associate

• Anthony Casso – underboss (1989–1994)
• Salvatore Santoro – underboss (1979–1986)
• Joseph Caridi – consigliere (2003–present)
• Louis Daidone – consigliere (1993–2003)
• Frank Lastorino – consigliere (1989–1993)
• Christopher Furnari – consigliere (1974–1987)
• Paul Vario – consigliere (1972–1979); capo
• Aniello Migliore – capo
• Joseph DiNapoli – capo
• Joseph Abate – capo
• Peter Chiodo – capo
• Anthony Accetturo – capo
• Salvatore Avellino – capo
• Michael Taccetta – capo
• Martin Taccetta – capo
• Salvatore Avellino – capo
• Johnny Dio – capo
• Joseph Testa - soldier
• Anthony Senter - soldier
• Nicodemo "Nicky" Scarfo Jr - capo
• Henry Hill – associate (Irish-Italian)
• Thomas "Tommy" DeSimone – associate
• Vincent Papa – associate
• Anthony Loria Sr. – associate

Boss/acting boss

• Nicolo Schiro – boss (1912–1930)
• Vito Bonventre – boss (1930)
• Salvatore Maranzano – boss (1930–1931)
• Joseph "Don Peppino" Bonanno – boss (1931–1965)
• Gaspar DiGregorio – boss (1965–1966)
• Paul Sciacca – boss (1966–1971)
• Natale Evola – boss (1971–1973); underboss (1968–1971)
• Carmine Galante – boss (1975–1979); underboss (1956–1962)
• Philip Rastelli – boss (1974–1975), (1979–1991); underboss (1970–1973)
• Joseph Massino – underboss (1981-1991), boss (1991–2004), became an informant
• Anthony Spero – acting boss (1987–1993)
• Vincent Basciano – acting boss (2004–2009)
• Salvatore Montagna – acting boss (2006–2009)

Underboss/consigliere/capo/soldier

• Salvatore Vitale – underboss (1991–2004); became an informant
• Richard Cantarella - acting underboss (2001-2002), became a government witness
• Nicholas Santora – acting underboss (2004-2007)
• Anthony Graziano – consigliere (2001–present)
• Dominick Napolitano – capo
• Alphonse Indelicato – capo
• Salvatore Bonanno – consigliere (1964–1966)
• Vincent Badalamenti - consigliere (2019–present)
• Michael Sabella – capo
• Philip Giaccone – capo
• Dominick Trinchera – capo
• Frank Coppa – capo
• Anthony Indelicato – capo
• Cesare Bonventre – soldier
• Benjamin "Lefty Guns" Ruggiero – soldier
• Thomas Pitera – soldier
• Anthony Mirra – soldier

Boss/acting boss

• Joseph Profaci – boss (1931–1961)
• Giuseppe Magliocco – underboss (1931–1962), boss (1962–1963)
• Joseph Colombo – boss (1963–1971)
• Carmine Persico – boss (1971–2019)
• Gennaro Langella – acting boss (1981–1984)
• Victor Orena – acting boss (1988–1992)
• Thomas Gioeli – acting boss (2001–present)
• Joel Cacace – acting boss (2000–2004)

Underboss/consigliere/capo/soldier

• John Franzese – underboss (1980–1995)
• Gennaro Langella – underboss (1972–1992)
• William Cutolo – underboss (1992–1999)
• John DeRoss – underboss (1999–2004)
• Carmine Sessa – consigliere (1988–1993)
• Charles Panarella – capo
• Vincenzo Aloi – capo
• Gregory Scarpa Sr. – capo
• Gregory Scarpa Jr. - capo
• Michael Franzese – capo
• Crazy Joe Gallo – soldier
• Ralph Scopo – soldier

Boss/acting boss

• James "Big Jim" Colosimo – boss (1903–1920)
• Johnny "The Fox" Torrio – boss (1920–1925)
• Al "Scarface" Capone – boss (1925–1931)
• Frank "The Enforcer" Nitti – boss (1932–1943)
• Paul Ricca – boss (1943–1947)
• Tony Accardo – boss (1947–1957)
• Sam "Momo" Giancana – boss (1957–1966)
• Sam Battaglia – boss (1966–1967)
• Jackie Cerone – boss (1967–1969)
• Felix Alderisio – boss (1969–1971)
• Joseph Aiuppa – boss (1971–1986)
• Joseph Ferriola – boss (1986–1989)
• Samuel Carlisi – boss (1989–1993)
• Joseph Lombardo – boss (1993–present)
• James Marcello – front boss (2003–2007)
• John DiFronzo – official boss (1996-2018)
• Salvatore DeLaurentis – acting boss (2014–2018) official boss (2018–present)

Boss/acting boss

• Frank Balistrieri – boss (1961–1993)

Underboss/consigliere/capo/soldier

Boss/acting boss

• Salvatore Sabella – boss (1911–1931)
• Joseph Ida – boss (1946–1959)
  • Antonio Pollina – acting boss (1958–1959)
• Angelo Bruno – boss (1959–1980)
• Philip Testa – boss (1980–1981)
• Nicodemo Scarfo – boss (1981–1991), consigliere (1980–1981)
• John Stanfa – boss (1991–1994)
• Joseph Merlino – boss (1994–present)
  • Ralph Natale – front boss (1994–1999)
  • Joseph Ligambi- acting boss (1999–2014), consigliere (2014-present)

Underboss/consigliere/capo/soldier

• Phil Leonetti – underboss (1986–1989)
• Frank Sindone – capo
• Salvatore Testa – capo
• Harry Riccobene – capo

Boss/acting boss

• Sam DeCavalcante – boss (1964–1976)
• Giovanni Riggi – boss (1970s–2015)
• John D'Amato – acting boss (1991–1992)
• Giacomo Amari – acting boss (1992–1994)
• Joseph Miranda – acting boss (2003–2006)
• Frank Guarraci – acting boss (2006–2016)
• Charles Majuri – official boss (2016–present)

Underbosses/consigliere/capo/soldier

• Girolamo Palermo – underboss (1976–1989)
• Giacomo Amari – underboss (1989–1994)
• Girolamo Palermo – underboss (1994–2000)
• Joseph Miranda – acting underboss (2003–2005) official underboss (2007–unknown)
• Frank Guarraci – capo
• Joseph Miranda – capo
• Gaetano Vastola – acting underboss (1990–1991)
• Vincent Palermo – capo
• Girolamo Palermo – capo
• Giuseppe Schifilliti – capo
• Philip Abramo – capo
• Anthony Capo – soldier
• Louis Consalvo – soldier

Boss/acting boss

• Gaspare Messina – boss (1916–1924)
• Raymond L.S. Patriarca – underboss (1938–1952), boss (1952–1984)
• Nicholas Bianco – underboss (1990–1991), boss (1991)
• Frank Salemme – boss (1991–2000)
• Luigi Mannochio – boss (2000–present)

Underboss/consigliere/capo/soldier/associate

• Enrico Tameleo – underboss (1952–1968)
• Matthew Guglielmetti – capo (1991–present)
• Vincent Ferrara – capo (1986–1989)
• Robert Carrozza – capo
• Ilario Zannino – consigliere (1984–1987)
• Angelo Mercurio – soldier
• Angiulo Brothers

Winter Hill Gang

• Stephen "The Rifleman" Flemmi - Underboss, FBI informant
• Vincent "Jimmy the Bear" Flemmi - associate, FBI informant
• Johnny Martorano - soldier, government witness

Boss/acting boss

• Salvatore Catalanotte – boss (1921–1930)
• Gaspar Milazzo – boss (1930)
• Cesare Lamare – boss (1930–1931)
• William Tocco – boss (1931–1936)
• Joseph Zerilli – boss (1936–1977)
• Jack Tocco – boss (1977–2014)

Underboss/consigliere

• Anthony Joseph Zerilli – underboss (1977–2015)
• William Tocco – underboss (1936–1963)
• Angelo Meli – consigliere (1950s-1969)

Boss/acting boss

• Stefano Magaddino – boss (1922–1974)
• Joseph Todaro Sr. – boss (1984–2006)
• Joseph Todaro Jr. – boss (2006–present); acting boss (1995–2006)

Boss/acting boss

• Vito Di Giorgio – boss (1909–1922)
• Rosario DeSimone – boss (1922–1925)
• Joseph Ardizzone – boss (1925–1931)
• Jack Dragna – boss (1931–1957)
• Frank DeSimone – boss (1957–1967)
• Nick Licata – boss (1967–1974)
• Dominic Brooklier – boss (1974–1984)
  • Jimmy Fratianno – acting boss (1975–1977)

Underboss/consigliere/capo

• Simone Scozzari – underboss (1956–1962)
• Joseph Dippolito – underboss (1967–1974)
• Carmen Milano – underboss (1984–2006)
• Tom Dragna – consigliere (1931–1956)
• Frank Bompensiero – capo (1933–1977)
• Louis Tom Dragna – capo (1947–1985)
• Jimmy Caci – capo (late 1970s–2011)
• Mike Rizzitello - capo (1977-1990)