4000 series (2001-2007)

In February 2001, Navistar released its all-new 4000 series, dubbed as "High Performance Trucks".^[5] Developed in the Blue Diamond Truck joint venture with Ford, the 4000 series marked the first completely new truck line from International since the 1979 S series. Sharing its chassis with the medium-duty Ford F-Series (introduced in 2000), the International 4300/4400 retained the DT466 and DT530 diesels of their predecessors. For versions equipped with automatic transmissions, electronics for the engine and transmissions were retuned to optimize throttle and shifting response, to increase both performance and fuel economy.^[6] To increase forward visibility, the size of the windshield was increased by over 60%, with additional attention paid to improvements in ventilation.^[7]

At the launch of the 4000 series, the standard 4300 and higher-GVWR 4400 were introduced as replacements for the previous 4900 model series.^[8] In 2002, the lower-GVWR 4200 was introduced as the replacement for the 4700 series, marking the introduction of the VT365 engine. In 2006, the 4100 was introduced, expanding the model line into the Class 5 segment; the model was discontinued a single year of production. The 4200, 4300, and 4400 were produced in both a standard and low-profile frame. The 4400 was also produced in a semitractor; sitting 4 inches higher than the chassis truck, the 4400 tractor was the only version offered with the DT570 engine as an option.

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  International 4200LP extended-cab
• 
  International 4400 crew cab
• 
  International 4300 crew cab
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  International 4400 semitractor
• 
  International DuraStar 4300

DuraStar (2008-2018)

For 2008, coinciding with the introduction of the International ProStar and International LoneStar, Navistar revised the branding of its truck model lines. In line with nomenclature previously used by International Harvester, truck lines adopted a "xxxxStar" naming scheme, with the 4000 series adopting the DuraStar model name. This change was completed in its entirety for the 2010 model year.^[15] In another revision, to comply with 2007 emissions regulations, the powertrain lineup underwent extensive revision, with the 6.0L VT365 V8 replaced by the 6.4L MaxxForce 7 V8. The DT inline-6 engine family underwent revisions as well, with the DT466 becoming the MaxxForce DT and the DT570 becoming the MaxxForce 9, adopting four-valve cylinder heads and exhaust gas recirculation to reduce emissions.

While each International model series retained the use of numerical model codes, after the model revision, their usage was highly downplayed, largely relegated to places such as the build plate for the vehicle. Externally, International replaced the numerical series and engine identification with script identifying the model series.

In 2010, the International TerraStar model line was introduced, effectively replacing the discontinued 4100 model line. Sharing the cab of the DuraStar, the TerraStar sat on a lower frame and wore its own hood.

Electric variant (eMV)

In 2021, Navistar announced a battery electric variant of the MV Series, the eMV.^[18] Navistar and Penske both announced on October 11, 2021, that Penske would be the first fleet in the United States to operate the eMV.^[19]

Bus

International 3300 bus chassis with school bus body

International 4400/DT570 with utility bed, International RXT is configured similar (with pickup-truck bed)

Like the 4000 series before it, the DuraStar serves as a popular platform for bus manufacturers, with two configurations sold for bus production. The International 3200 is a cutaway-cab chassis; the International 3300 is a cowled chassis. The former is sold primarily for commercial applications while the latter is sold nearly exclusively to Navistar subsidiary IC Bus, for both school bus and commercial applications.

Diesel–electric hybrid trucks

In 2007, Navistar International became the first American truck manufacturer to produce a diesel-electric truck, with the International DuraStar Hybrid. International Truck and Engine teamed with the Hybrid Truck Users Forum (HTUF), a consortium of utility industry customers, Eaton Corporation, the US Federal Government and the Calstart organization to assist with the cost of bringing the technology to market. It also provided direct customer feedback and support.^[20]

Pickup truck

From 2005 to 2008, International sold a factory-produced crew-cab pickup truck variant of the 4000 series. Named the International RXT (RXT=Recreational Extreme Truck), at 272 inches long, the truck was the longest-length pickup truck ever produced.for sale in North America. Unlike the 7000 series-derived CXT, the RXT was rear-wheel drive, marketed towards customers with large RV, boat, and horse trailers; both trucks source a pickup truck bed from the Ford F-350 Super Duty. Derived from the 4200, the RXT was powered by a 230 hp VT365 V8 and an Allison 2200 transmission.

In 2008, following lower than expected sales, the XT series was withdrawn.