Hepatocyte nuclear factor 4 gamma

HNF4G
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1LV2
Identifiers
Aliases	HNF4G, NR2A2, NR2A3, Hepatocyte nuclear factor 4 gamma
External IDs	OMIM: 605966 MGI: 1353604 HomoloGene: 37886 GeneCards: HNF4G
Gene location (Human)
Chr.	Chromosome 8 (human)
End	75,566,834 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	3,723,112 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; rectum; ; gallbladder; ; right lobe of liver; ; body of pancreas; ; islet of Langerhans; ; Achilles tendon; ; bronchial epithelial cell; ; kidney;
	Top expressed in
	duodenum; ; jejunum; ; urethra; ; ileum; ; male urethra; ; proximal tubule; ; intestinal villus; ; crypt of lieberkuhn of small intestine; ; colon; ; stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; steroid hormone receptor activity; sequence-specific DNA binding; DNA binding; nuclear receptor activity; zinc ion binding; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription by RNA polymerase II; intracellular receptor signaling pathway; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-templated; transcription, DNA-templated; steroid hormone mediated signaling pathway; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3174
	30942
	ENSG00000164749
	ENSMUSG00000017688
	Q14541
	Q9WUU6
	NM_004133; NM_001330561
	NM_013920; NM_001395870
	NP_001317490; NP_004124
	NP_038948; NP_001382799
	Wikidata
View/Edit Human	View/Edit Mouse

Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is encoded by the HNF4G gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164749 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000017688 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma".
↑ Drewes T, Senkel S, Holewa B, Ryffel GU (March 1996). "Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes". Molecular and Cellular Biology. 16 (3): 925–31. doi:10.1128/mcb.16.3.925. PMC 231074. PMID 8622695.
↑ Wisely GB, Miller AB, Davis RG, Thornquest AD, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP (September 2002). "Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids". Structure. 10 (9): 1225–34. doi:10.1016/S0969-2126(02)00829-8. PMID 12220494.

External links

FactorBook HNF4G

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000164749 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000017688 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: HNF4G hepatocyte nuclear factor 4, gamma".

[pmid8622695-6] Drewes T, Senkel S, Holewa B, Ryffel GU (March 1996). "Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes". Molecular and Cellular Biology. 16 (3): 925–31. doi:10.1128/mcb.16.3.925. PMC 231074. PMID 8622695.

[pmid12220494-7] Wisely GB, Miller AB, Davis RG, Thornquest AD, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP (September 2002). "Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids". Structure. 10 (9): 1225–34. doi:10.1016/S0969-2126(02)00829-8. PMID 12220494.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

See also

References

Further reading

External links