Giacomo ([ˈdʒaːkomo]) is an Italian given name corresponding to English James. It is the Italian version of the Hebrew name Jacob.

People bearing the name include:

• Giacomo Acerbo (1888–1969), Italian economist and Fascist politician
• Giacomo Agostini (born 1942), Italian motorcycle road racer
• Giacomo Antonelli (1806–1876), Italian cardinal
• Giacomo Aragall (born 1939), Catalan tenor
• Giacomo Balla (1871–1958), Italian painter
• Giacomo Barozzi da Vignola (1507–1573), Italian Mannerism architect
• Giacomo Beltrami (1779–1855), Italian jurist, author, and explorer
• Giacomo Biffi (1928–2015), Italian cardinal
• Giacomo Bonaventura (born 1989), Italian footballer
• Giacomo Boni (archaeologist) (1859–1925), Italian archaeologist specializing in Roman architecture
• Giacomo Boni (painter) (1688–1766), Italian painter of the late-Baroque period, active mainly in Genoa
• Giacomo Brodolini (1920–1969), Italian politician
• Giacomo Carissimi (1605–1674), Italian Baroque composer
• Giacomo Casanova (1725–1798), Venetian adventurer and author
• Giacomo Ceruti (1698–1767), Italian late Baroque painter
• Giacomo Colombo (1663–1730) Italian late Baroque sculptor, working in Naples.
• Giacomo Doria (1840–1913), Italian naturalist
• Giacomo Durazzo (1717–1794), Italian diplomat and man of the theatre
• Giacomo Feo (c. 1471–1495), second husband of Caterina Sforza
• Giacomo Ferrara (born 1990), actor
• Giacomo Ferrari (disambiguation), multiple people
• Giacomo Gastaldi (ca 1500–1566), Italian cartographer
• Giacomo di Grassi, 16th century Italian fencing master and author
• Giacomo Lauri-Volpi (1892–1979), Italian tenor who performed throughout Europe and the Americas
• Giacomo da Lentini (13th century), Italian poet
• Giacomo Leone (born 1971), Italian long-distance runner
• Giacomo Leoni (1686–1746), Italian architect
• Giacomo Leopardi (1798–1837), Italian poet, essayist, philosopher, and philologist
• Giacomo Lercaro (1891–1976), Italian cardinal
• Giacomo Manzù (1908–1991), Italian sculptor
• Giacomo Matteotti (1885–1924), Italian socialist parliamentarian, murdered by Fascists for his opposition to Mussolini
• Giacomo Medici (general) (1817–1882), Italian patriot and soldier
• Giacomo Meyerbeer (1791–1864), German-born opera composer
• Giacomo Nizzolo (born 1989), Italian road cyclist
• Giacomo della Porta (c. 1533–1602), Italian architect and sculptor
• Giacomo Puccini (1858–1924), Italian composer
• Giacomo Quarenghi (1744–1817), Italian architect
• Giacomo Raspadori (born 2000), Italian footballer
• Giacomo Ricci (born 1985), Italian racing driver
• Giacomo Sagripanti, Italian conductor
• Giacomo Tomaselli (born 1999), Italian footballer