GPA may refer to:

Education

• Grade point average
• Grace Preparatory Academy, in Arlington, Texas, United States
• Government Polytechnic Amravati, in Maharashtra, India

Government and politics

• Agreement on Government Procurement of the World Trade Organization
• Gambia Ports Authority
• Georgia Ports Authority, in the U.S. state of Georgia
• Government Property Agency (Hong Kong)
• Government Property Agency (United Kingdom)
• Green Party of Alberta
• Guam Power Authority

Science and medicine

• Generalized Procrustes analysis
• Geometric phase analysis
• Gigapascal (GPa), a unit of pressure
• Glenopolar angle
• Gradient pattern analysis
• Granulomatosis with polyangiitis
• Gravida/para/abortus, in medicine
• Gravity Probe A (GP-A), an experiment to test the theory of general relativity
• Guanidinopropionic acid
• Proton affinity

Sport

• Gaelic Players Association
• Gambia Ports Authority FC
• Gibraltar Pistol Association
• Gross Production Average, in baseball

Other uses

• GPA (company), a Brazilian retailer
• Araxos Airport, serving Patras, Greece
• Ford GPA, an amphibious vehicle
• Gay Police Association, in the United Kingdom
• Global Peace Agency, a fictional DC Comics organization
• Guinness Peat Aviation, a defunct Irish company
• GNU Privacy Assistant, a graphical frontend to GNU Privacy Guard
• Personal Service Workers' Union, a former Austrian trade union