Francesco Santafede (16th century) was an Italian painter of the Renaissance period, active mainly in Naples. He was the father of the painter Fabrizio Santafede, a pupil of Andrea Sabbatini (Andrea di Salerno). He was a colleague of Francesco Imparato, and like his son, emerged from the studio of Andrea Sabbatini, although he appears to have also followed the style of Giovanni Filippo Criscuolo.

References

• De Dominici, Bernardo (1742). Vite dei Pittori, Scultori, ed Architetti Napolitani (2 volumes). Nalples: Stamperia del Ricciardi. pp. 147–149.