| Phasmaviridae | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Ellioviricetes |
| Order: | Bunyavirales |
| Family: | Phasmaviridae |
Phasmaviridae is a family of viruses with negative stranded RNA genomes associated with insect hosts. They are a member of the order Bunyavirales.[1] Phasmaviruses were first discovered in phantom midges of the genus Chaoborus in 2014.[2]
Taxonomy
The family contains the following six genera:[1]
- Feravirus
- Hymovirus
- Jonvirus
- Orthophasmavirus
- Sawastrivirus
- Wuhivirus
Ferak feravirus
Ferak feravirus, a member of the genus Feravirus, has been isolated in cell culture. The virion is enveloped and spherical with a diameter of 80–120 nanometers. The genome has three segments L (6.8 kilobases), M (4.2 kilobases) and S (1.5 kilobases). It encodes five proteins—the polymerase on the L segment, the p12G and the Gc-Gn protein on the M segment and the N and p12 proteins in the S segment.[3]
A Gn–Gc glycoprotein dimer binds to the cell receptor. The virus is endocytosed and escapes into the cytoplasm where it replicates. It is released from the cell by budding.[3]
References
- 1 2 "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 19 May 2021.
- ↑ Ballinger, M. J.; Bruenn, J. A.; Hay, J.; Czechowski, D.; Taylor, D. J. (2014-08-15). "Discovery and Evolution of Bunyavirids in Arctic Phantom Midges and Ancient Bunyavirid-Like Sequences in Insect Genomes". Journal of Virology. 88 (16): 8783–8794. doi:10.1128/JVI.00531-14. ISSN 0022-538X. PMC 4136290. PMID 24850747.
- 1 2 Marklewitz M, Zirkel F, Kurth A, Drosten C, Junglen S (2015) Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family. Proc Natl Acad Sci USA 112(24):7536–7541. doi: 10.1073/pnas.1502036112
External links