Ezio is an Italian masculine name, originating from the Latin name Aetius.

It may refer to:

• Flavius Aetius (c. 396–454), Roman general, after whom Metastasio's libretto and all the operas below are named.
  • Ezio (libretto), opera libretto by Metastasio. Notable settings are:
    • Ezio (Handel), King's Theatre, London 1732
    • Ezio (Mysliveček, 1775), Naples
    • Ezio (Mysliveček, 1777), Munich – completely new music
    • Ezio (Gluck), Prague 1750, revised Vienna 1763
    • Ezio (Traetta) by Tommaso Traetta, Teatro delle Dame, Rome, 1757
    • Ezio (Latilla), Naples 1758
• Ezio (band), a band from Cambridge, England
• Ezio Gamba (born 1958), an Italian judoka
• Ezio Mauro (born 1948), an Italian journalist
• Ézio (footballer) (1966-2011), Ézio Leal Moraes Filho, Brazilian footballer
• Ezio Vanoni (1903–1956), Italian economist and politician
• Ezio Vigorelli (1892–1964), Italian lawyer and politician

Fictional characters

• Ezio Auditore da Firenze, the protagonist of Ubisoft's Assassin's Creed II, Assassin's Creed Brotherhood and Assassin's Creed Revelations

See also

• Ezio (security), a security solution range for online banking and shopping from Gemalto
• EZ-IO, an intraosseous infusion drill by Vidacare
• Ezio (Flavius Aetius), character from Verdi's Attila (opera)